DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-epsilon and si:ch211-74m13.1

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_001922015.4	Gene:	si:ch211-74m13.1 / 100149459	ZFINID:	ZDB-GENE-081104-12	Length:	328	Species:	Danio rerio

Alignment Length:	349	Identity:	73/349 - (20%)
Similarity:	124/349 - (35%)	Gaps:	99/349 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 VKLACSVKNLGSYKVAWMHFEQSAILTVHNHVITRNPRISVTHDKHDKHRTWFLHINNVQEEDRG 133
            |.|..:||  |:.....:......::...|...:.|...|||||    ...|...:..|.
Zfish    12 VTLLVTVK--GTNAECPLQINPPKLVVRFNSSASANCNTSVTHD----GMGWEATVGGVP----- 65

  Fly   134 RYMCQINTVTAKT---------------QYG-FVKVVVPPNI---DDALTSSDI--IVREGDNVT 177
              :.:.|.:|.:.               .|| ..:|.:|..|   .|:::.|.:  |:.||:...
Zfish    66 --LSKANLITWRVSQLTDWKIEPPFCYINYGKQCEVPLPVTIYKTPDSVSISTVNQIMTEGNQYE 128

  Fly   178 LRC---KAKGSPEPTIKWKR----------DDGNKIVINKTLE--VH-DLETDSLELERISRLHM 226
            |:|   ....:...||.|.:          .|..|..:||.:.  :| |...|..:....:.|::
Zfish   129 LQCDIHNVAPAQNLTINWYKGETLVNQTNFTDNTKSPVNKIIRLLIHPDRADDGAQYRCETELNL 193

  Fly   227 GAYLCIASNGVPP-SVSKRIKVSVDFSPMVWIPH--QLVGIPIGFNITLECFIEANPTSLNYWTR 288
            |    :.....|| :.||.:.:.|.:.|.    |  ....|.....:.|.|.::|||.::..|..
Zfish   194 G----VEGPQPPPKNTSKPLSIDVHYKPQ----HSSSAENISQSDTVYLNCTVKANPAAVYTWHS 250

  Fly   289 ENDQMITESSKYKTETIPGHPSYKATMRLTITNVQSSDY--GNYKCVAKNPRGDMDGNIKLYMSS 351
            |:   :.|                   :::...:|||..  |.|.|.|.|   |:..:.|:::.|
Zfish   251 EH---LKE-------------------KISSPVIQSSPLSPGKYTCTATN---DLGASSKVFIVS 290

  Fly   352 PPTTQPPPTTTTLRRTTTTAAEIA 375
                       :..|||..|..||
Zfish   291 -----------SAGRTTFWAIVIA 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	19/101 (19%)
		Ig	69..139	CDD:143165	14/69 (20%)
		IG_like	165..249	CDD:214653	22/102 (22%)
		IGc2	172..237	CDD:197706	16/80 (20%)
		IG_like	267..348	CDD:214653	18/82 (22%)
		Ig	270..339	CDD:299845	16/70 (23%)
si:ch211-74m13.1	XP_001922015.4	Ig2_ICAM-1_like	109..209	CDD:143232	23/103 (22%)
		Ig_2	217..281	CDD:290606	20/92 (22%)
		IG_like	230..281	CDD:214653	17/75 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910