DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DIP-epsilon and si:ch73-208g10.1

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_001091731.1	Gene:	si:ch73-208g10.1 / 100002730	ZFINID:	ZDB-GENE-040108-6	Length:	899	Species:	Danio rerio

Alignment Length:	345	Identity:	79/345 - (22%)
Similarity:	130/345 - (37%)	Gaps:	96/345 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 GSTLNNVISEDPEFTDVIE---NIT-------VPAGRNVKLACSVK-NLG--------------- 79
            |.||.|    ...|||..:   |||       |.|....:..|..: |||
Zfish   539 GETLVN----QTNFTDTTKSPVNITSYLLIHPVRADNGAQFRCETELNLGEEGPQPPPKNTSKPL 599

  Fly    80 SYKV----------AWMHFEQSAI--LTVHNHVITRNPRISVTHDKHDKHRTWFLHIN-NVQEED 131
            |..|          .|...:.|::  ...|.|.:..||..|::.    ||.:..::.: .:.|.|
Zfish   600 SIPVHYAPEIKSCQPWSPKKGSSLDSYPKHLHSVVGNPHPSISW----KHNSSPVNASAPLTETD 660

  Fly   132 RGRYMCQINTVTAKTQYGFVKVVVPPNIDDALTSSDIIVREGDNVTLR-----CKAKGSPEPTIK 191
            .|:|     .:||...||.....:...::   .|.::|..|...|..:     |..:|.|:|.:.
Zfish   661 SGQY-----EITASNHYGESNCTISITVE---YSPELICEESYEVKEKTVFSPCDVEGEPKPELS 717

  Fly   192 WKRDDGNKIVINKTLEVHDLETDSLELERISRLHMGAYLCIASN--GVPPSVSKRIKVSVDFSPM 254
            ..: :|.:|.:....:.:|               .|.|...|.|  |   ||:|.:.::|.::|.
Zfish   718 LYK-EGKRIQLFNGFKWND---------------SGLYQLTARNKHG---SVNKSLTINVQYAPR 763

  Fly   255 VWIPHQLVGIPIGFNITLECFIEANPTSLNYWTRENDQMITESSKYKTETIPGHPSYKATMRLTI 319
            ::...|...:...:.|.|:|....||....:|: .|::.|:...:|.|..|.     |||
Zfish   764 LFASQQDFVVAKDYRIILQCNSSGNPEPEMWWS-FNNKNISTGRRYITFNIE-----KAT----- 817

  Fly   320 TNVQSSDYGNYKCVAKNPRG 339
                |:..|||.|:|:|..|
Zfish   818 ----STSAGNYTCIARNEIG 833

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	28/134 (21%)
		Ig	69..139	CDD:143165	19/98 (19%)
		IG_like	165..249	CDD:214653	19/90 (21%)
		IGc2	172..237	CDD:197706	13/71 (18%)
		IG_like	267..348	CDD:214653	22/73 (30%)
		Ig	270..339	CDD:299845	21/68 (31%)
si:ch73-208g10.1	NP_001091731.1	Ig	105..207	CDD:299845
		Ig	299..401	CDD:299845
		Ig2_ICAM-1_like	499..599	CDD:143232	16/63 (25%)
		Ig	635..684	CDD:299845	13/57 (23%)
		IG_like	693..758	CDD:214653	17/83 (20%)
		IGc2	701..748	CDD:197706	11/62 (18%)
		I-set	769..843	CDD:254352	23/80 (29%)
		Ig	776..843	CDD:299845	22/73 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910