| Sequence 1: | NP_001137877.1 | Gene: | Snup / 7354429 | FlyBaseID: | FBgn0259199 | Length: | 351 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001036046.1 | Gene: | SNUPN / 10073 | HGNCID: | 14245 | Length: | 360 | Species: | Homo sapiens |
| Alignment Length: | 313 | Identity: | 111/313 - (35%) |
|---|---|---|---|
| Similarity: | 165/313 - (52%) | Gaps: | 41/313 - (13%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 18 QQKQRQKELLKQQKLR--------RQQEQDDYRPLQNQEKPVPRKKSGKRSGHQ--KGIP--YRP 70
Fly 71 Q--LSEWLRHKPDDL-NEWLLVPCPVGKRCLVVASKGITKAYSKGGWMFVNFRSSLPGDWQ---L 129
Fly 130 QKGETILDCVYVEDADTFYVLDAISFGLQEVQECEASFRFYWLRARF-EEHDYDKISENNEKKFK 193
Fly 194 LLDHFDFEDPSAVEQALHKYPFFPENKPDLDGFLFYHKEASYVCRETPLVCWLFPFMMEDVLG-- 256
Fly 257 LPVNKCYKAPEDYQPSHVLQYMDAFEQKLAEHRRTLKE--QKKKVNEQKEDPH 307 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Snup | NP_001137877.1 | Snurportin-1_C | 71..249 | CDD:185717 | 76/184 (41%) |
| SNUPN | NP_001036046.1 | Necessary for interaction with XPO1. /evidence=ECO:0000269|PubMed:10209022 | 1..159 | 47/122 (39%) | |
| Necessary for interaction with KPNB1 and m3G-cap U1 and U5 snRNP import receptor activity. /evidence=ECO:0000269|PubMed:18187419, ECO:0000269|PubMed:9670026 | 1..65 | 7/25 (28%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..42 | 1/2 (50%) | |||
| Snurportin1 | 25..64 | CDD:314440 | 6/24 (25%) | ||
| Snurportin-1_C | 97..280 | CDD:185717 | 77/188 (41%) | ||
| Interaction with m3G-cap structure. /evidence=ECO:0000269|PubMed:15920472, ECO:0007744|PDB:1XK5 | 127..129 | 1/1 (100%) | |||
| Necessary for binding to the m3G-cap structure. /evidence=ECO:0000269|PubMed:9670026 | 208..328 | 42/134 (31%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 339..360 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165152574 | |
| Domainoid | 1 | 1.000 | 149 | 1.000 | Domainoid score | I4437 |
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 156 | 1.000 | Inparanoid score | I4303 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG59432 | |
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0006152 | |
| OrthoInspector | 1 | 1.000 | - | - | oto90563 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_104267 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR13403 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X4438 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 11 | 10.900 | |||||