Protein Alignment CG42300 and NSMCE2

DIOPT Version :10

• Sequence 1: NP_727865.2
• Gene: CG42300 / 7354426
• FlyBaseID: FBgn0259196
• Length: 181
• Species: Drosophila melanogaster
• Sequence 2: XP_016868819.1
• Gene: NSMCE2 / 286053
• HGNCID: 26513
• Length: 249
• Species: Homo sapiens
• Alignment Length: 200
• Identity: 45/200 - (22%)
• Similarity: 80/200 - (40%)
• Gaps: 40/200 - (20%)

  Fly     3 KMDPKSHQKLFKEMAEVVSNSSDDGEKLLTKNSSNTIEKSEEVCKERPEAVEQMRIDVNN---SL 64
            |.:..|...:.|.|.|..  :.|.......|...:||...:|   ||||.:..:::.|..   :|
Human    54 KAEVSSEYSMDKAMVEFA--TLDRQLNHYVKAVQSTINHVKE---ERPEKIPDLKLLVEKKFLAL 113

  Fly    65 EDTNMNAVESEAQKNI------------------------AGLDEDLIMEDFGVEVVPFHDPWSK 105
            :..|.:|.....:|.:                        .|:|||:|:..   ....|..|.:|
Human   114 QSKNSDADFQNNEKFVQFKQQLKELKKQCGLQADREADGTEGVDEDIIVTQ---SQTNFTCPITK 175

  Fly   106 LLIKHPVRNKRCGHIYDRETVLMII----KDNIGILCPVRDCPNLSDIKLEHLVKDPDVEQELQK 166
            ..:|.||:||.|||.|:.:.::.:|    |......||...|.: :||:...|::|..:.:.::.
Human   176 EEMKKPVKNKVCGHTYEEDAIVRMIESRQKRKKKAYCPQIGCSH-TDIRKSDLIQDEALRRAIEN 239

  Fly   167 RKSDK 171
            ....:
Human   240 HNKKR 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42300	NP_727865.2	SPL-RING_NSE2	102..166	CDD:438313	20/67 (30%)
NSMCE2	XP_016868819.1	SPL-RING_NSE2	169..239	CDD:438313	21/70 (30%)