DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nsun5 and nsun5

DIOPT Version :9

Sequence 1:	NP_650787.1	Gene:	Nsun5 / 7354421	FlyBaseID:	FBgn0259704	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	XP_009303671.1	Gene:	nsun5 / 406690	ZFINID:	ZDB-GENE-040426-2476	Length:	483	Species:	Danio rerio

Alignment Length:	443	Identity:	148/443 - (33%)
Similarity:	226/443 - (51%)	Gaps:	58/443 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 YRATAKILKAALEQQKCIKTLIFAEKHARTRSLHTVLKKFSENRVALEKAIEETGLLRDNPSFDP 78
            |...|:||:...:::..:|||::..|....:.|..::.:..:....|::.|..|.||::. ....
Zfish     4 YLKAAEILEKVEQKRGAVKTLVYDSKFPNIKQLFALVCETQKYSSVLQEIINSTKLLKET-KLRI 67

  Fly    79 SLAKILVTELLFGR-KELNGESKPVQTVRSYKDRLLNSIRDFGVQRK-----------------E 125
            .|||:||.:||.|. .:..|..|  .|:..::.||..::....::||                 :
Zfish    68 HLAKVLVYDLLIGHGVKCGGAWK--TTMLKHRARLQAALARIKIKRKVSRNQDLLPSSIQQTQND 130

  Fly   126 PNPRYVRINTNLYSLAEALDYLHKSDWRRKELPADASYADFLTAIKSLAENEFMTDLHVEGVLIF 190
            ..|||||:||...||.:.:|||.:..:..:..|..      |..:..|:...|:.|||::.:|:|
Zfish   131 VIPRYVRVNTLKTSLEDVIDYLKREGFSYQGTPGR------LEDLDRLSGKMFLCDLHLKDLLVF 189

  Fly   191 PAKWSNYWVRHPLVHSKRFILQNKATCLAAELLAPPSGATVLDMCAAPGMKTVHICNVMQNKGCI 255
            ..|...:  .|.|..:...|||.||:||.|.||.||.|:.|:|.|||||.||.|:..:|:|||.:
Zfish   190 SGKTDFH--DHFLYKAGHIILQGKASCLPAFLLNPPVGSHVIDACAAPGNKTSHLAAIMKNKGKL 252

  Fly   256 YSVEQDHVRYNTLCEITKDAGCDIVKPILGDALNLTPE--RFPDVEYILVDPSCSGSGMQNRMTV 318
            ::.:.|..|.:|:..:...||....|....|.|.:.|:  .:.:|:|||:|||||||||     |
Zfish   253 FAFDLDAKRLSTMSTLLLRAGVTCHKLANQDFLKVDPQNSEYKEVKYILLDPSCSGSGM-----V 312

  Fly   319 C-----DEPKEDKRLQKLQGLQIKILSHAMGAFPNVKRIAYCTCSLWKEENEQVVQRCLQLNPSF 378
            |     .|.:||.|||.|...|:..|:||: .||.::||.|.|||:..:|||:||..|||.||.|
Zfish   313 CLRDELPETQEDGRLQALAAFQLHCLNHAL-QFPQLERIVYSTCSIHSQENEEVVTACLQRNPGF 376

  Fly   379 KLLSCKKALRNKWHNVGDKDYPNIGKNVL-YCQPDSDL---TDGIFLALFEKR 427
            :|:          |.:  .|:|..|...| .|...|..   |.|.|:|:.|:|
Zfish   377 RLV----------HLL--PDWPERGHEPLTQCLRASTAKTRTHGFFVAMLERR 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nsun5	NP_650787.1	RsmB	<124..428	CDD:223222	120/332 (36%)
nsun5	XP_009303671.1	nop2p	136..416	CDD:188051	114/305 (37%)
nsun5	XP_009303671.1	AdoMet_MTases	217..414	CDD:302624	86/214 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590424
Domainoid	1	1.000	135	1.000	Domainoid score	I4942
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	203	1.000	Inparanoid score	I3710
OMA	1	1.010	-	-		QHG53910
OrthoDB	1	1.010	-	-		D1128973at2759
OrthoFinder	1	1.000	-	-		FOG0003757
OrthoInspector	1	1.000	-	-		oto39622
orthoMCL	1	0.900	-	-		OOG6_102591
Panther	1	1.100	-	-	LDO	PTHR22807
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1816
SonicParanoid	1	1.000	-	-		X3119
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.900