DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nsun5 and Nop2

DIOPT Version :9

Sequence 1:	NP_650787.1	Gene:	Nsun5 / 7354421	FlyBaseID:	FBgn0259704	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	NP_001178714.1	Gene:	Nop2 / 314969	RGDID:	1304616	Length:	772	Species:	Rattus norvegicus

Alignment Length:	409	Identity:	98/409 - (23%)
Similarity:	163/409 - (39%)	Gaps:	120/409 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 GRKELNGESKPVQTVRSYKDRLLNSIRDFGVQRKEPNPRYVRINTNLYSLAEALDYLHKSDWRRK 155
            |:.:.:.::..:|.|......::..:||||.||:|...|              .:||.:   .:|
  Rat   205 GQTDQDAQTPDLQRVHKRIQDIVGVLRDFGAQREEGRSR--------------TEYLSQ---LQK 252

  Fly   156 ELPADASYADFLTA-----------IKSLAENEFMTDLHV------------------EGVLIFP 191
            :|....||.|||.:           |:.|..||....:.:                  .||.:.|
  Rat   253 DLATYYSYGDFLLSKLMELFPLSELIEFLEANEVPRPITLRTNTLKTRRRDLAQALINRGVNLDP 317

  Fly   192 -AKWS-----------------NYWVRHPLVHSKRFILQNKATCLAAELLAPPSGATVLDMCAAP 238
             .|||                 .|...|       ::||..::.|....|||.....:||||.||
  Rat   318 LGKWSKSGLVVYDSSVPIGATPEYLAGH-------YMLQGASSMLPVMALAPQEHERILDMCCAP 375

  Fly   239 GMKTVHICNVMQNKGCIYSVEQDHVRYNTLCEITKDAGCDIVKPILGD--ALNLT--------PE 293
            |.||.:|..:|:|.|.|               :..||..:.:|.::|:  .|.:|        ..
  Rat   376 GGKTSYIAQLMKNTGVI---------------LANDANAERLKSVVGNLHRLGVTNTIVSHYDGR 425

  Fly   294 RFPDV----EYILVDPSCSGSGMQNRMTVCDEPKEDKRLQKLQGLQIKILSHAMGAFPNVKR--- 351
            :||.|    :.:|:|..|||:|:.::.......|::|.:|:...||.::|..|:.:.....:
  Rat   426 QFPKVVGGFDRVLLDAPCSGTGVISKDPAVKTNKDEKDIQRCAHLQKELLLSAIDSVNAASKTGG 490

  Fly   352 -IAYCTCSLWKEENEQVV-----QRCLQLNPS---FKLLSCKKALRNKWHNVGDKDYPNIGKNVL 407
             :.|||||:..||||.||     :|.::|.|:   |......:....::|       |.:.....
  Rat   491 YLVYCTCSITVEENEWVVDYALKKRNVRLVPTGLDFGQEGFTRFRERRFH-------PTLRATRR 548

  Fly   408 YCQPDSDLTDGIFLALFEK 426
            : .|.:...||.|:|.|:|
  Rat   549 F-YPHTHNMDGFFIAKFKK 566

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nsun5	NP_650787.1	RsmB	<124..428	CDD:223222	89/376 (24%)
Nop2	NP_001178714.1	Methyltr_RsmF_N	<279..353	CDD:293730	13/80 (16%)
		nop2p	292..566	CDD:188051	73/303 (24%)
		Nol1_Nop2_Fmu	357..565	CDD:279522	61/230 (27%)
		PRK10905	573..>761	CDD:236792
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0144
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810