DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nsun5 and Nsun5

DIOPT Version :9

Sequence 1:	NP_650787.1	Gene:	Nsun5 / 7354421	FlyBaseID:	FBgn0259704	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	XP_038945143.1	Gene:	Nsun5 / 288595	RGDID:	1309268	Length:	510	Species:	Rattus norvegicus

Alignment Length:	441	Identity:	147/441 - (33%)
Similarity:	228/441 - (51%)	Gaps:	50/441 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 YRATAKILKAALEQQKCIKTLIFAEKHARTRSLHTVLKKFSENRVALEKAIEETGLLRDNPSFDP 78
            |...|.:|.....:|..:|.|:::......:.|:.::.:.......|:..|...||||......|
  Rat     4 YATAAAVLAGVESRQGSLKGLVYSSNFQNLKQLYALVCETQRYSAVLDAVIASAGLLRAEKKLRP 68

  Fly    79 SLAKILVTELLFGRKELNGESKPVQTVRSYKDRLLNSIRDF----GVQRKE------PN-----P 128
            .|||:||.|||.|:....|..:....:..::.||...:...    ||.|.|      |.     |
  Rat    69 HLAKVLVYELLLGKGFRGGGGRWKALLGRHQARLKAELARLKVHRGVSRNEDLLQERPGQAHQVP 133

  Fly   129 RYVRINTNLYSLAEALDYLHKSDWRRKELPADASY---ADFLTAIKSLAENEFMTDLHVEGVLIF 190
            |:||:||......:|:||..:..:         ||   |..|..:::|....|:.|..:..:|:|
  Rat   134 RFVRVNTLKTCPEDAIDYFKRQGF---------SYQGRASSLEDLRTLKGQHFLLDPLLPELLVF 189

  Fly   191 PAKWSNYWVRHPLVHSKRFILQNKATCLAAELLAPPSGATVLDMCAAPGMKTVHICNVMQNKGCI 255
            ||:...:  .|||..:...|||:||:||.|.||:||.|:.|:|.|||||.||.:|..:::|:|.|
  Rat   190 PAQTDLH--EHPLYRAGHLILQDKASCLPAMLLSPPPGSHVIDACAAPGNKTSYIAALLKNQGKI 252

  Fly   256 YSVEQDHVRYNTLCEITKDAG---CDIVKPILGDALNLTP--ERFPDVEYILVDPSCSGSGMQNR 315
            ::.:||..|...:..:...||   |::.:.   |.|.::|  :|:..|:|||:|||||||||.:|
  Rat   253 FAFDQDAKRLAAMATLLARAGVSCCEVAEK---DFLTVSPSDQRYGQVQYILLDPSCSGSGMLSR 314

  Fly   316 MTVCDEPKE----DKRLQKLQGLQIKILSHAMGAFPNVKRIAYCTCSLWKEENEQVVQRCLQLNP 376
            .  .:|..|    .:|||.|.|.|.:.|.||: .||:::|:.|.||||.:||||.|||..||.|.
  Rat   315 Q--LEEHGEGTPSKERLQALAGFQQRALCHAL-RFPSLQRLVYSTCSLCQEENEDVVQEALQQNS 376

  Fly   377 -SFKLLSCKKALRNKWHNVGDKDYPNIGKNVLYCQPDSDLTDGIFLALFEK 426
             :|:|    ..:...|.:.|...:|. .::.|...|::.||.|.|:|:||:
  Rat   377 GTFRL----APVLPTWPHRGLSTFPG-SEHCLRASPETTLTGGFFIAVFER 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nsun5	NP_650787.1	RsmB	<124..428	CDD:223222	118/327 (36%)
Nsun5	XP_038945143.1	RsmB	45..422	CDD:223222	140/400 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349202
Domainoid	1	1.000	133	1.000	Domainoid score	I4960
eggNOG	1	0.900	-	-		E1_COG0144
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	205	1.000	Inparanoid score	I3660
OMA	1	1.010	-	-		QHG53910
OrthoDB	1	1.010	-	-		D1128973at2759
OrthoFinder	1	1.000	-	-		FOG0003757
OrthoInspector	1	1.000	-	-		oto95472
orthoMCL	1	0.900	-	-		OOG6_102591
Panther	1	1.100	-	-	LDO	PTHR22807
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3119
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.770