DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nsun5 and Nop2

DIOPT Version :9

Sequence 1:	NP_650787.1	Gene:	Nsun5 / 7354421	FlyBaseID:	FBgn0259704	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	NP_620086.2	Gene:	Nop2 / 110109	MGIID:	107891	Length:	794	Species:	Mus musculus

Alignment Length:	409	Identity:	102/409 - (24%)
Similarity:	164/409 - (40%)	Gaps:	120/409 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 GRKELNGESKPVQTVRSYKDRLLNSIRDFGVQRKEPNPRYVRINTNLYSLAEALDYLHKSDWRRK 155
            |..:.:|::..:|.|......::..:||||.||:|...|           ||.|..|      :|
Mouse   210 GETDQDGQAPDLQRVHKRIQDIVGVLRDFGAQREEGRSR-----------AEYLSRL------QK 257

  Fly   156 ELPADASYADFLTA-----------IKSLAENEFMTDLHV------------------EGVLIFP 191
            :|....||.|||.:           |:.|..||....:.:                  .||.:.|
Mouse   258 DLATYYSYGDFLLSKLMELFPLSELIEFLEANEVPRPITLRTNTLKTRRRDLAQALINRGVNLDP 322

  Fly   192 -AKWS-----------------NYWVRHPLVHSKRFILQNKATCLAAELLAPPSGATVLDMCAAP 238
             .|||                 .|...|       ::||..::.|....|||.....:||||.||
Mouse   323 LGKWSKSGLVVYDSSVPIGATPEYLAGH-------YMLQGASSMLPVMALAPQEHERILDMCCAP 380

  Fly   239 GMKTVHICNVMQNKGCIYSVEQDHVRYNTLCEITKDAGCDIVKPILGD--ALNLT--------PE 293
            |.||.:|..:|:|.|.|               :..||..|.:|.::|:  .|.:|        ..
Mouse   381 GGKTSYIAQLMKNTGVI---------------LANDANADRLKSVVGNLHRLGVTNTIISHYDGR 430

  Fly   294 RFPDV----EYILVDPSCSGSGMQNRMTVCDEPKEDKRLQKLQGLQIKILSHAMGAFPNVKR--- 351
            :||.|    :.:|:|..|||:|:.::.......|::|.:|:...||.::|..|:.:.....:
Mouse   431 QFPKVVGGFDRVLLDAPCSGTGVISKDPAVKTNKDEKDIQRCAHLQKELLLSAIDSVNAASKTGG 495

  Fly   352 -IAYCTCSLWKEENEQVV-----QRCLQLNPS---FKLLSCKKALRNKWHNVGDKDYPNIGKNVL 407
             :.|||||:..||||.||     :|.::|.|:   |......:....::|       |.: ::..
Mouse   496 YLVYCTCSITVEENEWVVDYALKKRNVRLVPTGLDFGQEGFTRFQARRFH-------PTL-RSTR 552

  Fly   408 YCQPDSDLTDGIFLALFEK 426
            ...|.:...||.|:|.|:|
Mouse   553 RFYPHTHNMDGFFIAKFKK 571

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nsun5	NP_650787.1	RsmB	<124..428	CDD:223222	92/376 (24%)
Nop2	NP_620086.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..194
		nop2p	297..571	CDD:188051	74/303 (24%)
		S-adenosyl-L-methionine binding. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01023	377..383		4/5 (80%)
		PHA03247	<577..794	CDD:223021
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0144
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810