DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nsun5 and Nsun5

DIOPT Version :9

Sequence 1:	NP_650787.1	Gene:	Nsun5 / 7354421	FlyBaseID:	FBgn0259704	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	XP_036020581.1	Gene:	Nsun5 / 100609	MGIID:	2140844	Length:	589	Species:	Mus musculus

Alignment Length:	443	Identity:	148/443 - (33%)
Similarity:	229/443 - (51%)	Gaps:	52/443 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 YRATAKILKAALEQQKCIKTLIFAEKHARTRSLHTVLKKFSENRVALEKAIEETGLLRDNPSFDP 78
            |.|.|.:|.....:|..:|.|:::......:.|:.::.:.......|:..|...||||......|
Mouse     4 YAAAAAVLAGVESRQGSLKGLVYSSNFQNLKQLYALVCETQRYSAVLDAVIASAGLLRAEKKLRP 68

  Fly    79 SLAKILVTELLFGRKELNGESKPVQTVRSYKDRLLNSIRDF----GVQRKE--------PN---- 127
            .|||:||.|||.|:....|..:....:..::.||...:...    ||.|.|        |.
Mouse    69 HLAKVLVYELLLGKGFRGGGGRWKALLGRHQARLKAELARLKVHRGVSRNEDLLQESSRPGQAYQ 133

  Fly   128 -PRYVRINTNLYSLAEALDYLHKSDWRRKELPADASY---ADFLTAIKSLAENEFMTDLHVEGVL 188
             ||:||:||......:|:||..:..:         ||   |..|..:::|....|:.|..:..:|
Mouse   134 VPRFVRVNTLKTRPEDAIDYFKRQGF---------SYQGRASSLEDLRALKGQHFLLDPLLPELL 189

  Fly   189 IFPAKWSNYWVRHPLVHSKRFILQNKATCLAAELLAPPSGATVLDMCAAPGMKTVHICNVMQNKG 253
            :|||:...:  .|||..:...|||:||:||.|.||:||.|:.|:|.|||||.||.:|..:::|:|
Mouse   190 VFPAQTDLH--EHPLYRAGHLILQDKASCLPAMLLSPPPGSHVIDACAAPGNKTSYIAALLKNQG 252

  Fly   254 CIYSVEQDHVRYNTLCEITKDAG---CDIVKPILGDALNLTP--ERFPDVEYILVDPSCSGSGMQ 313
            .|::.:||..|...:..:...||   |::.:.   |.|.::|  :|:..|:|||:|||||||||.
Mouse   253 KIFAFDQDAKRLAAMATLVARAGVSCCELAEK---DFLTVSPSDQRYSQVQYILLDPSCSGSGML 314

  Fly   314 NRMTVCDEPKE----DKRLQKLQGLQIKILSHAMGAFPNVKRIAYCTCSLWKEENEQVVQRCLQL 374
            :|.  .:|..|    .:|||.|.|.|.:.|.||: .||:::|:.|.||||.:||||.|||..||.
Mouse   315 SRQ--LEEHGEGTPSKERLQALAGFQQRALCHAL-RFPSLQRLVYSTCSLCQEENEDVVQEALQH 376

  Fly   375 NP-SFKLLSCKKALRNKWHNVGDKDYPNIGKNVLYCQPDSDLTDGIFLALFEK 426
            |. :|:|    ..:...|.:.|...:|. .::.|...|::.||.|.|:|:||:
Mouse   377 NSGTFRL----APVLPTWPHRGLSTFPG-SEHCLRASPETTLTGGFFIAVFER 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nsun5	NP_650787.1	RsmB	<124..428	CDD:223222	118/329 (36%)
Nsun5	XP_036020581.1	RsmB	45..424	CDD:223222	140/402 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845785
Domainoid	1	1.000	133	1.000	Domainoid score	I5072
eggNOG	1	0.900	-	-		E1_COG0144
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	206	1.000	Inparanoid score	I3718
Isobase	1	0.950	-	0	Normalized mean entropy	S2551
OMA	1	1.010	-	-		QHG53910
OrthoDB	1	1.010	-	-		D1128973at2759
OrthoFinder	1	1.000	-	-		FOG0003757
OrthoInspector	1	1.000	-	-		oto91896
orthoMCL	1	0.900	-	-		OOG6_102591
Panther	1	1.100	-	-	LDO	PTHR22807
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1816
SonicParanoid	1	1.000	-	-		X3119
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.750