DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir7f and grik1a

DIOPT Version :9

Sequence 1:	NP_001138177.1	Gene:	Ir7f / 7354418	FlyBaseID:	FBgn0259188	Length:	621	Species:	Drosophila melanogaster
Sequence 2:	XP_009303592.1	Gene:	grik1a / 798001	ZFINID:	ZDB-GENE-030131-6502	Length:	919	Species:	Danio rerio

Alignment Length:	466	Identity:	84/466 - (18%)
Similarity:	174/466 - (37%)	Gaps:	80/466 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   204 NTFDG---RKWKASQMFPDKLSQMHGCPLTVLTWHQPPFVELVWDPK--HNRSRGSGFEIQLVEH 263
            |::.|   .:.|.::...|.|:..   .|.|.|..:.|:|......|  :...|..|:.:.|::.
Zfish   424 NSYTGLNLTEIKDNKNITDSLANR---TLIVTTILENPYVMYKKSDKVLYGNDRFEGYCLDLLKE 485

  Fly   264 LARRMNFSLELVNIALLRPNAY--RLAEGSSEGPIEKLLQRNVNISMGYFRKTARRNQLLTTPMS 326
            |:..:.|:.|   :.|:....|  :..:|...|.:.:|:....::::.....|..|.:::.....
Zfish   486 LSNILGFTYE---VKLVTDGKYGAQNDKGEWNGMVRELIDHIADLAVAPLTITYVREKVIDFSKP 547

  Fly   327 YYSANLVAVLQLERYRIGSLALLVFPFELSVWMLLLLALLIHLGIHLPSARRG-----NEEDGGG 386
            :.:..:..:.:........:...:.|....:||.:|||.|....:....||..     |......
Zfish   548 FMTLGISILYRKPNGTNPGVFSFLNPLTPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNP 612

  Fly   387 GLQVV--------ALLLG-AALAR-----LPRSWRHRFIAAHWLWASIPLRISYQSLLFHLIRLQ 437
            ..:||        :|..| |||.|     :|::...|.:...|.:.::.:..||.:.|...:.::
Zfish   613 SSEVVENNFTLLNSLWFGVAALMRQGSELMPKALSTRILGGIWWFFTLIIISSYTANLAAFLTVE 677

  Fly   438 LYNTPSFSLDQLLAEGFQGICTANTQRLLLEMPQLARDPDSI----QSVDTPFD--WDVLN---- 492
            ..::|..|.|.|            .::..:|...: ||..::    :|..:.::  |..::
Zfish   678 RMDSPIDSADDL------------AKQTRIEYGAV-RDGSTMTFFKKSKISTYEKMWAFMSSRKN 729

  Fly   493 -VLTRNRNRKIFAVANQDVTLSFLHSSAHPNAFHVVKQPVNVEYA---------GMYMPKHSFLY 547
             .|.:|....|..|...|..|....:|..    ::.::..|:...         |:..|..|...
Zfish   730 TALVKNSKDGITRVLTTDYALLMESTSIE----YITQRNCNLTQVGGLIDSKGYGVGTPIGSPYR 790

  Fly   548 EKMDDDIRRLDASGFIHA-----WRRASFASVHRKEQVHMTSRRYINHAKLSGIYMVMAGLYLLA 607
            :|:...|.:|...|.:|.     ||.........||      ...:....:.||::|:|...:|:
Zfish   791 DKVTIAILQLQEEGKLHMMKEKWWRGNGCPEEDSKE------ASALGVENIGGIFIVLAAGLVLS 849

  Fly   608 GLLFAGEVLLR 618
            ..:..||.:.:
Zfish   850 VFVAIGEFIYK 860

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir7f	NP_001138177.1	Periplasmic_Binding_Protein_Type_2	231..>358	CDD:304360	19/130 (15%)
grik1a	XP_009303592.1	Periplasmic_Binding_Protein_Type_1	37..432	CDD:299141	2/7 (29%)
		ANF_receptor	57..398	CDD:279440
		Periplasmic_Binding_Protein_Type_2	446..815	CDD:304360	68/391 (17%)
		Lig_chan	577..846	CDD:278489	56/291 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900