DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Ir7f and grid2

DIOPT Version :9

Sequence 1:NP_001138177.1 Gene:Ir7f / 7354418 FlyBaseID:FBgn0259188 Length:621 Species:Drosophila melanogaster
Sequence 2:NP_001004123.1 Gene:grid2 / 448841 ZFINID:ZDB-GENE-040913-1 Length:1009 Species:Danio rerio


Alignment Length:472 Identity:102/472 - (21%)
Similarity:166/472 - (35%) Gaps:122/472 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   222 SQMHGCPLTVLTWHQPPFV----ELVWDPKHNRSRGSGFEIQLVEHLARRMNFSLELVNIALLRP 282
            :.|.|..|.|:|..:.|||    .::..||    :..||.|.:::.||..:.|..| :.:|....
Zfish   436 NNMRGVVLRVVTVLEEPFVMVSENVLGKPK----KYQGFSIDVLDALANYLGFKYE-IYVAPDHK 495

  Fly   283 NAYRLAEGSSEGPIEKLLQRNVNISMGYFRKTARRNQLL--TTPMSYYSANLVAVLQLERYRIGS 345
            ...:.|:|:..|.|.:|:.:..::.:.....|..|..::  ||....||   |.||..:..|...
Zfish   496 YGSQQADGTWNGLIGELVFKRADVGLSALTITPERESVVDFTTRYMDYS---VGVLLRKAERTVD 557

  Fly   346 LALLVFPFELSVW-----MLLLLALLIHLGIHLPSAR------------------RGNEEDGGGG 387
            :...:.||:||:|     .:||:..|::|...|...|                  .|:....||.
Zfish   558 MFACLAPFDLSLWACIAGTVLLVGTLVYLLNWLNPPRLPMGSVSSTTLYNSMWFVYGSFVQQGGE 622

  Fly   388 LQVVALLLGAALARLPRSWRHRFIAAHWLWASIPL--------------RI--SYQSLLFHLIRL 436
            :....|    |...:...|        ||:|.|.:              ||  |.|||.....:.
Zfish   623 VPYTTL----ATRMMMGVW--------WLFALIVISSYTANLAAFLTISRIENSIQSLQDLAKQT 675

  Fly   437 QL-YNT--PSFSLDQLLAEGFQGICTANTQRLLLEMPQLARDPDSIQSVDTPFDWDVLNVLTRNR 498
            .| |.|  .|...||:.::|               |....|||...|.      |.::|......
Zfish   676 DLPYGTVLDSAVYDQVRSKG---------------MNPFERDPMYSQM------WRMINRTGGAE 719

  Fly   499 N---------RKI----FAVANQDVTLSFLHSSAHPNAFHVVKQPVNVEYAGMYMPKHSFLYEKM 550
            |         ||:    ||.......|.::..:....:.:.|...|.....||.| :|...|..:
Zfish   720 NNVEESKEGIRKVKYGRFAFVWDAAVLEYVAINDEDCSLYTVSNNVADRGYGMAM-QHGSPYRDI 783

  Fly   551 ------------DDDIRRLDASGFIHAWRRASFASVHRKEQVHMTSRRYINHAKLSGIYMVMAGL 603
                        |.||.:|      ..|.|.|...::.......:......|: .:|::.|:|..
Zfish   784 FSQRILELQQNGDMDILKL------KWWPRDSPCDLYSPVGTRKSGSALDIHS-FAGVFFVLAAG 841

  Fly   604 YLLAGLLFAGEVLLRQR 620
            .:|:.|:...|....:|
Zfish   842 VVLSCLIATVETWWTRR 858

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ir7fNP_001138177.1 Periplasmic_Binding_Protein_Type_2 231..>358 CDD:304360 34/132 (26%)
grid2NP_001004123.1 PBP1_iGluR_delta_2 28..427 CDD:107386
ANF_receptor 42..404 CDD:279440
PBP2_iGluR_delta_2 440..806 CDD:270449 90/413 (22%)
Lig_chan 568..841 CDD:278489 62/313 (20%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 989..1009
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1052
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.