DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir7f and gria3b

DIOPT Version :9

Sequence 1:	NP_001138177.1	Gene:	Ir7f / 7354418	FlyBaseID:	FBgn0259188	Length:	621	Species:	Drosophila melanogaster
Sequence 2:	NP_938174.1	Gene:	gria3b / 368416	ZFINID:	ZDB-GENE-030616-53	Length:	883	Species:	Danio rerio

Alignment Length:	281	Identity:	48/281 - (17%)
Similarity:	108/281 - (38%)	Gaps:	50/281 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   203 VNTFDGRKWKASQMFPDKLSQMHGCPLTVLTWHQPPFVELVWDPKHNRSRGS----GFEIQLVEH 263
            ||..|       |.|.:..|.:....:.|.|..:.|:|  ::...|....|:    |:.:.|...
Zfish   396 VNIMD-------QQFTNDSSSVENRTIVVTTIMEAPYV--MYKKNHMHLEGNEKYEGYCVDLASE 451

  Fly   264 LARRMNFSLELVNIALLRPNAYRLAEGSSE---GPIEKLLQRNVNISMGYFRKTARRNQLLTTPM 325
            :|:.:.....|   :::....|...:..::   |.:.:|:....:|::.....|..|.:::....
Zfish   452 IAKHVGIKYRL---SIVMDGKYGARDPETKSWNGMVGELVYGRADIAVAPLTITLVREEVIDFSK 513

  Fly   326 SYYSANL-VAVLQLERYRIGSLALLVFPFELSVWMLLLLALLIHLGIHL---------PSARRGN 380
            .:.|..: :.:.:.::.:.|..:.| .|....:||.::.|   ::|:.:         |...:.:
Zfish   514 PFMSLGISIMIKKPQKSKPGVFSFL-DPLAYEIWMCIVFA---YIGVSVVLFLVSRFSPYEWQLD 574

  Fly   381 EED-------------GGGGLQVVALLLGAALAR----LPRSWRHRFIAAHWLWASIPLRISYQS 428
            |.|             ..|....:...|||.:.:    .|||...|.:...|.:.::.:..||.:
Zfish   575 ETDEVKDPQTPPDPPNDFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTA 639

  Fly   429 LLFHLIRLQLYNTPSFSLDQL 449
            .|...:.::...:|..|.:.|
Zfish   640 NLAAFLTVERMVSPIESAEDL 660

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir7f	NP_001138177.1	Periplasmic_Binding_Protein_Type_2	231..>358	CDD:304360	20/134 (15%)
gria3b	NP_938174.1	Periplasmic_Binding_Protein_Type_1	25..396	CDD:299141	48/281 (17%)
		ANF_receptor	36..379	CDD:279440
		PBP2_iGluR_AMPA	412..794	CDD:270433	42/258 (16%)
		Lig_chan	544..824	CDD:278489	22/120 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810