DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir7f and Ir40a

DIOPT Version :9

Sequence 1:	NP_001138177.1	Gene:	Ir7f / 7354418	FlyBaseID:	FBgn0259188	Length:	621	Species:	Drosophila melanogaster
Sequence 2:	NP_610140.4	Gene:	Ir40a / 35449	FlyBaseID:	FBgn0259683	Length:	732	Species:	Drosophila melanogaster

Alignment Length:	726	Identity:	134/726 - (18%)
Similarity:	237/726 - (32%)	Gaps:	196/726 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 VLAQLSTTLVVTISTRHLGTAHWFEYMMNILMDSWRMVAVQLLRIRPDLVVNPVPGRKRVSLLMV 117
            :|..|::|.:..|......||.....::..|..|    ::.:|.: |.|.::....:|..::.:.
  Fly    13 LLGLLNSTRLTFIGNDESDTAIALTQIVRGLQQS----SLAILAL-PSLALSDGVCQKERNVYLD 72

  Fly   118 DSYQGLLDTNITASNANFDDPDYYFIFLQARDHLIPKELQLILD---------------HCLAHF 167
            |..|.|..:|.  .:..|...:.:|..::.......:.:.||||               |.|:.|
  Fly    73 DFLQRLHRSNY--KSVVFSQTELFFQHIEENLQGANECISLILDEPNQLLNSLHDRHLGHRLSLF 135

  Fly   168 -------WLHCNVMIQTAQ-VEVLVYT---------YYPYTADACQKAYPIPVNTFDGRKWKASQ 215
                   |...:.:|:..: :.|:|.|         || ..|..|..:....||.:||......:
  Fly   136 IFYWGARWPPSSRVIRFREPLRVVVVTRPRKKAFRIYY-NQARPCSDSQLQLVNWYDGDNLGLQR 199

  Fly   216 --MFPDKLS---QMHGCPLTVLTWHQPPFVELVW-------DPKHN----------RSRGSGFEI 258
              :.|..||   ...|....|..:|.||:..:.:       |.:.|          |..| |.:.
  Fly   200 IPLLPTALSVYANFKGRTFRVPVFHSPPWFWVTYCNNSFEEDEEFNSLDSIEKRKVRVTG-GRDH 263

  Fly   259 QLVEHLARRMNFSLELVNIALLRPNAYRLAEG-----SSEGPIEKLLQRNVNISMGYFRKTARRN 318
            :|:..|::.|||..:.:........:.|..:|     |..|.|..|.....:..:|....:..|.
  Fly   264 RLLMLLSKHMNFRFKYIEAPGRTQGSMRSEDGKDSNDSFTGGIGLLQSGQADFFLGDVGLSWERR 328

  Fly   319 QLLTTPMSYYS-ANLVAVLQLERYRIGSLALLVFPFELSVWMLLLLALLI--------------- 367
            :.:  ..|::: |:..|.......|:.....::.||:..:|..|:|.::.
  Fly   329 KAI--EFSFFTLADSGAFATHAPRRLNEALAIMRPFKQDIWPHLILTIIFSGPIFYGIIALPYIW 391

  Fly   368 ----------HLG---IHL-------PSARRGNEEDGGGGLQV------------VALLLGAALA 400
                      |||   ||:       |...:..........|:            :.|.|..:..
  Fly   392 RRRWANSDVEHLGELYIHMTYLKEITPRLLKLKPRTVLSAHQMPHQLFQKCIWFTLRLFLKQSCN 456

  Fly   401 RLPRSWRHRFIA-AHWLWASIPLRISYQSLLFH-------------LIRLQ---------LYNTP 442
            .|...:|.:|:. .:|:.|:..|...|.:.|..             |.|||         ||...
  Fly   457 ELHNGYRAKFLTIVYWIAATYVLADVYSAQLTSQFARPAREPPINTLQRLQAAMIHDGYRLYVEK 521

  Fly   443 SFSLDQLLAEGFQGICTANTQRLLLEMPQLARDPDS--IQSVDTPFDWDVLNVLTRNRNRKIFAV 505
            ..|..::|..|.:    ...|...|...|:..||..  |.||:...              |:.|.
  Fly   522 ESSSLEMLENGTE----LFRQLYALMRQQVINDPQGFFIDSVEAGI--------------KLIAE 568

  Fly   506 ANQD-------VTLSFLHSSAHPNAFHVVKQPVNVEYAGMYMPKHSFLYEKMDDDIRRLDASGFI 563
            ..:|       .||.|.......|.|. :.|.:...|:.:.:.........:::.:.:|..||.:
  Fly   569 GGEDKAVLGGRETLFFNVQQYGSNNFQ-LSQKLYTRYSAVAVQIGCPFLGSLNNVLMQLFESGIL 632

  Fly   564 HAWRRASFASVH----------------------RKEQVHMTSRRYINHAKLSGIYMVMAGLYLL 606
            .....|.:|..:                      |.|....|....:|...|.|.::.:.
  Fly   633 DKMTAAEYAKQYQEVEATRIYKGSVQAKNSEAYSRTESYDSTVISPLNLRMLQGAFIALG----- 692

  Fly   607 AGLLFAGEVLL 617
            .|.|.||.:||
  Fly   693 VGSLAAGVILL 703

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir7f	NP_001138177.1	Periplasmic_Binding_Protein_Type_2	231..>358	CDD:304360	28/149 (19%)
Ir40a	NP_610140.4	PBP2_LTTR_substrate	216..338	CDD:330233	23/124 (19%)
		Periplasmic_Binding_Protein_Type_2	297..>391	CDD:328725	15/95 (16%)
		Periplasmic_Binding_Protein_Type_2	<496..637	CDD:328725	30/159 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463006
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42643
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940