DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir7f and Ir7b

DIOPT Version :9

Sequence 1:	NP_001138177.1	Gene:	Ir7f / 7354418	FlyBaseID:	FBgn0259188	Length:	621	Species:	Drosophila melanogaster
Sequence 2:	NP_572410.2	Gene:	Ir7b / 31690	FlyBaseID:	FBgn0029965	Length:	655	Species:	Drosophila melanogaster

Alignment Length:	626	Identity:	147/626 - (23%)
Similarity:	259/626 - (41%)	Gaps:	109/626 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 SIYKSYLENSRIDMQGEDANLYVARALRLVIEN-VLAQLSTTLVVTISTRHLGTAHWFEYMMNIL 83
            |:..|.:|:|      .|.:|  |.||..|:.| .:.:..|..:.|.:.......|..|.:..:|
  Fly    12 SLVASTMESS------SDWDL--AEALAQVVANSEMGRFKTLYIYTHTNSQSTGGHLEELLDQVL 68

  Fly    84 M------DSWRMVAVQLLRIRPDLVVNPVPGRKRVSLLMVDSYQGLLDTNITASNANFDDPDYYF 142
            |      .:.|::..|.:..:|  .|:.|       |.:||....|  :.|.|......|..:..
  Fly    69 MIVPNNLQARRLLLQQSMEYKP--YVHAV-------LALVDGLPSL--SAIYARIRATQDLSHTL 122

  Fly   143 IFLQARDHLIPKELQLILDHCLAHFW----LHCNVMIQTAQVEVLVYTYYPYTA-DACQKAYPIP 202
            |::........:|:|.    .|...|    |:..|:::.....:|:.:|:|::| ..||......
  Fly   123 IYMSMPTDAYGEEMQA----TLRFLWRLSVLNVGVVLRPPGDHILMVSYFPFSALHGCQVISANV 183

  Fly   203 VNTFD--GRKWKASQMFPDKLSQMHGCPLTVLTWHQPPFVELVWDPKHNRSRGS--GFEIQLVEH 263
            ||.:.  .::|.:...||.||...:||.||..||...|:  |||.|.   ..||  |.|..|::.
  Fly   184 VNRYQVGTKRWASQDYFPSKLGNFYGCLLTCATWEDMPY--LVWRPD---GSGSFVGIEGALLQF 243

  Fly   264 LARRMNFSLELVNIALLRPNAYR-LAEGSSEGPI-EKLLQRNVNISMG--YFRKTARRNQLLTTP 324
            :|..:||:     :.|...|... ||.....|.| :::...:.:.|:|  :|:.:|......:..
  Fly   244 MAENLNFT-----VGLYWMNKEEVLATFDESGRIFDEIFGHHADFSLGGFHFKPSAGSEIPYSQS 303

  Fly   325 MSYYSANLVAVLQLERYRIGSLALLVFPFELSVW-----MLLLLALLIHLGIHLPSARRGNEEDG 384
            ..|:.::::.|..|:. ...:...|.|||...:|     :|:|..||:.|   |...|..:|...
  Fly   304 TYYFMSHIMLVTNLQS-AYSAYEKLSFPFTPLLWRAIGLVLILACLLLML---LVRWRHHHELPR 364

  Fly   385 GGGLQVVALLLGAALAR--LPRSWRHRFIAAHWLWASIPLRISYQSLLFHLIRLQLYNTPSFSLD 447
            ....:::.|.:|..|..  :|:.:..|.:...||:|::.||..|||.::.|:|......|..::.
  Fly   365 NPYYELLVLTMGGNLEDRWVPQRFPSRLVLLTWLFATLVLRSGYQSGMYQLLRQDTQRNPPQTIS 429

  Fly   448 QLLAEGFQ-GICTANTQRLLLEMPQLARDPDSIQSVDTPFDWDVLNVLTRNRNRKIFAVANQDVT 511
            ::||:.|. .:...|..|:|..:|:|.  |:.            |..|..:..:...|:|.|.
  Fly   430 EVLAQHFTIQLAEVNEARILASLPELR--PEQ------------LVYLEGSELQSFPALAQQS-- 478

  Fly   512 LSFLHSSA-----------------HP--NAFHVVKQPVNVEYAGMYMPKHSFLYEKMDDDIRRL 557
                .|||                 ||  ...|:|::.:..:....|:.:||.|...::..|:..
  Fly   479 ----GSSARVAILTPYEYFGYFRKVHPMSRRLHLVRERIYTQQLAFYVRRHSHLVGVLNKQIQHA 539

  Fly   558 DASGFIHAWRRASFASVHRKEQ--VHMTSRRYINHAKLSGI 596
            ...||:..|.|...::|..|::  ..:.|..|   :.|.||
  Fly   540 HTHGFLEHWTRQYVSAVDEKDESVARIASTSY---STLDGI 577

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir7f	NP_001138177.1	Periplasmic_Binding_Protein_Type_2	231..>358	CDD:304360	32/132 (24%)
Ir7b	NP_572410.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463107
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25775
OrthoDB	1	1.010	-	-		D71073at33392
OrthoFinder	1	1.000	-	-		FOG0007621
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42643
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.960