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Protein Alignment Ir7f and GRIA4

DIOPT Version :9

Sequence 1:	NP_001138177.1	Gene:	Ir7f / 7354418	FlyBaseID:	FBgn0259188	Length:	621	Species:	Drosophila melanogaster
Sequence 2:	NP_000820.4	Gene:	GRIA4 / 2893	HGNCID:	4574	Length:	902	Species:	Homo sapiens

Alignment Length:	462	Identity:	75/462 - (16%)
Similarity:	169/462 - (36%)	Gaps:	91/462 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   219 DKLSQMHGCP-------------LTVLTWHQPPFVELVWDPKHNRSRGS----GFEIQLVEHLAR 266
            |||..:...|             :.|.|..:.|:|  ::...|....|:    |:.:.|...:|:
Human   394 DKLVLIQDVPTLGNDTAAIENRTVVVTTIMESPYV--MYKKNHEMFEGNDKYEGYCVDLASEIAK 456

  Fly   267 RMNFSLELVNIALLRPNAYRLAEGSSE---GPIEKLLQRNVNISMGYFRKTARRNQLLTTPMSYY 328
            .:....:   ||::....|...:..::   |.:.:|:.....|::.....|..|.:::.....:.
Human   457 HIGIKYK---IAIVPDGKYGARDADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFM 518

  Fly   329 SANL-VAVLQLERYRIGSLALLVFPFELSVWMLLLLALLIHLGIHL---------PSARRGNE-E 382
            |..: :.:.:.::.:.|..:.| .|....:||.::.|   ::|:.:         |......| |
Human   519 SLGISIMIKKPQKSKPGVFSFL-DPLAYEIWMCIVFA---YIGVSVVLFLVSRFSPYEWHTEEPE 579

  Fly   383 DGGGG-----------LQVVALLLGAALAR----LPRSWRHRFIAAHWLWASIPLRISYQSLLFH 432
            ||..|           ...:...|||.:.:    .|||...|.:...|.:.::.:..||.:.|..
Human   580 DGKEGPSDQPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAA 644

  Fly   433 LIRLQLYNTPSFSLDQLL--AEGFQGICTANTQRLLLEMPQLARDPDSIQSVDTPFD--WDVL-- 491
            .:.::...:|..|.:.|.  .|...|...:.:.:......::|           .::  |..:
Human   645 FLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIA-----------VYEKMWTYMRS 698

  Fly   492 ---NVLTRNRNRKIFAVANQDVTLSFLHSSAHPNAFHVVKQP---------VNVEYAGMYMPKHS 544
               :|.||.....:..|.......:||..|. .|.:...::|         ::.:..|:..||.|
Human   699 AEPSVFTRTTAEGVARVRKSKGKFAFLLEST-MNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGS 762

  Fly   545 FLYEKMDDDIRRLDASGFIHAWRRASF---ASVHRKEQVHMTSRRYINHAKLSGIYMVMA---GL 603
            .|...::..:.:|..:|.:...:...:   .....|:.........::.:.::|::.::.   ||
Human   763 SLRTPVNLAVLKLSEAGVLDKLKNKWWYDKGECGPKDSGSKDKTSALSLSNVAGVFYILVGGLGL 827

  Fly   604 YLLAGLL 610
            .:|..|:
Human   828 AMLVALI 834

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.