DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir7f and glr-3

DIOPT Version :9

Sequence 1:	NP_001138177.1	Gene:	Ir7f / 7354418	FlyBaseID:	FBgn0259188	Length:	621	Species:	Drosophila melanogaster
Sequence 2:	NP_492017.3	Gene:	glr-3 / 172449	WormBaseID:	WBGene00001614	Length:	836	Species:	Caenorhabditis elegans

Alignment Length:	451	Identity:	86/451 - (19%)
Similarity:	167/451 - (37%)	Gaps:	104/451 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   219 DKLSQMHGCPLTVLTWHQPPFVELVWDPKHNRSRGS--GFEIQLVEHLARRMNFSLELVNIALLR 281
            :||: :.|..|.:..:.:.|||.:.       |.||  |:.|.|:..:|..:.|:   ..|..:|
Worm   394 EKLT-LEGKHLKISVYLEAPFVMIT-------SNGSYEGYCIDLLHKIANILKFT---YTIQKVR 447

  Fly   282 PNAY--RLAEGSSEGPIEKLLQRNVNISMGYFRKTARRNQLLTTPMSYYSANLVAVLQLERYRIG 344
            .|||  :.:.|...|.:.:|.:.:.::::.....:..|::::...:.|....:..:.:..|.|..
Worm   448 DNAYGSKESNGKWSGMVGELQRGDADLAVASLTISYGRSEVIDFTVPYMHLGISILFKKPRIRDS 512

  Fly   345 SLALLVFPFELSVWMLLLLA-LLIHLGIHL-----PSARRGNEEDGGGGLQV------------- 390
            .....:.|....||::...: .::.:.|.:     |..:...:||.|....|
Worm   513 DWFKFMDPLSTQVWIMTFASYFVVSVAIWIIAKISPYEQFERDEDNGQYKPVDNQFSLRNSFWFT 577

  Fly   391 VALLLGAALARLPRSWRHRFIAAHWLWASIPLRISYQSLLFHLIRLQLYNTPSFSLDQLLAE--- 452
            |..|:.......||:...|.:...|.:.::.|..||.:.|..::..:...||..:.|.|.|:
Worm   578 VCSLMQQGSELCPRAASTRLLTGIWWFFALILISSYTANLAAVLTTRRMETPIENADDLAAQTKI 642

  Fly   453 --GFQGICTANTQRLLLEMPQLARDPDSIQSVDTPFDWDVLN----VLTRNRNRKIFAVANQDVT 511
              |..|  ..:|.....|        ..|::.:..  |.:::    :..::....|..|.:.|
Worm   643 KYGTLG--RGSTMSFFNE--------SKIETYERM--WQLMSSSPGLFVQSSKEGIARVKSSD-- 693

  Fly   512 LSFLHSSAHPNAFHVVKQPVNVEYA-------------------GMYMPKHSFLYEKMDDDIRRL 557
            .::|..|:            .:|||                   |:.:||.|...|.:...|.||
Worm   694 YAYLMESS------------MLEYAVERDCELMQIGGLIDQKGYGIGLPKGSPYRELISTAILRL 746

  Fly   558 DASGFIHA-----WRRASFA--SVHRKEQVHMTSRRYINHAKLSGIYMVM-AGLYLLAGLL 610
            .....:..     |:..|..  ...||:|....|        :.||:::: .||.|.|.|:
Worm   747 QEKTELTELKEKWWKDKSVVCEQPKRKDQDDGES--------IGGIFIILVVGLVLTAVLV 799

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir7f	NP_001138177.1	Periplasmic_Binding_Protein_Type_2	231..>358	CDD:304360	24/130 (18%)
glr-3	NP_492017.3	PBP1_iGluR_non_NMDA-like	21..385	CDD:380591
glr-3	NP_492017.3	Periplasmic_Binding_Protein_Type_2	401..761	CDD:419667	70/395 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810