Protein Alignment Ir7e and grik5

DIOPT Version :9

• Sequence 1: NP_001138176.1
• Gene: Ir7e / 7354417
• FlyBaseID: FBgn0259189
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: NP_001315085.1
• Gene: grik5 / 798791
• ZFINID: ZDB-GENE-070821-6
• Length: 1067
• Species: Danio rerio
• Alignment Length: 708
• Identity: 120/708 - (16%)
• Similarity: 231/708 - (32%)
• Gaps: 259/708 - (36%)

  Fly    12 DLSGEQMNHINEFVARAVLHVVHHYILSVTPSLVLTLCCRSNHTCNFY--NKMMSTLF------- 67
            |:..||.|    .|..::.:..|.:.|....|  |.|..|.....|.|  ..:.|.|.
Zfish   269 DIVDEQSN----IVGFSMFNTTHPFYLEFIRS--LNLSWREGCDINPYPGPALSSALLFDAVHVV 327

  Fly    68 ----------REWGLAPL------------QIVNVLRGVPWHPVPGRRHFNVIFTDSFAAFEEIR 110
                      :|.|:.||            .::|.||.|.:..:.||..||
Zfish   328 VSAVQELNRSQEIGVKPLSCTSPQIWQHGTSLMNYLRMVEYDGLTGRVEFN-------------- 378

  Fly   111 MEYYSREYNYNEHYFIFLQARDRLLQGEMRLIFDYCWRYRLIHCSIQVQKSNGDILFYSYYPFGE 175
              ...:..||..|          :|:           ::|..|..|.:..||..:|..|
Zfish   379 --SKGQRTNYTLH----------ILE-----------KHRGGHKEIGIWYSNNTLLMNS------ 414

  Fly   176 HGCSDMEPQLINRYNGSMLVEPDLFPRKLRNFFGCPLRCALWDVPPFLTLDEDQEEVLRVNGGYE 240
               :.::..:........|:...:    |.|              |::....:.:| ...|..||
Zfish   415 ---TSLDINVSETLANKSLIITTI----LEN--------------PYVMRKINYQE-FEGNEQYE 457

  Fly   241 G---RLLLALAEKMNFTIAVRKVHVNMRDEAL---------------EMLRRDEVDLTLGGIRQT 287
            |   .:|..|::.:.||..::.|     |:.|               |::.| :.||.:.....|
Zfish   458 GFCVDMLRELSDILKFTYRIKLV-----DDGLYGAPEPNGSWTGMVGELINR-KADLAVAAFTIT 516

  Fly   288 VARGMVATSSHNYHQTREVFGVLASS--YEL------SSFDILFYPYRLQIWM-GILGVVALSAL 343
            ..|..|...|       :.|..|..|  |.:      ..|..| .|:...:|: .:|..:|:|.:
Zfish   517 SEREKVIDFS-------KPFMTLGISILYRVHIGRKPGYFSFL-DPFSPAVWLFMLLAYLAVSCV 573

  Fly   344 IQLIVGRM-----------LRER---------MGSRFWLNL-ELVFVGMPLLECPRSHTARLYCV 387
            : .:..|:           ||||         :|:..|..: ..:..|..::  ||:.:.|....
Zfish   574 L-FLSARLSPYEWYNPHPCLRERRDLLENQYTLGNSLWFPVGGFMQQGSEIM--PRALSTRCVSG 635

  Fly   388 MLMMYTLIIRTIYQGLLYHLIRTHQLNRWPQTIESLVQKNFTVVLTPIVQEVLDEIPSVQHMRFR 452
            :...:||||.:.|...|...:...::.                  .||  |..|::....::::.
Zfish   636 VWWAFTLIIISSYTANLAAFLTVQRME------------------VPI--ESPDDLADQTNIQYG 680

  Fly   453 LLEANSELDPLYFLEANHQLRQ----HVTASALDIFIHFNRLSADKVHQRGEQGSGAHFEIVPED 513
            .:...|.:  .:|:.:.:|..|    ::.:....:|:           :..|:|...
Zfish   681 TIHGGSTM--TFFMNSRYQTYQRMWNYMYSKQPSVFV-----------KSTEEGIAR-------- 724

  Fly   514 IISMQLTMYLAKHSFLI--------------------------------------DQLNEEIMWM 540
            :::       :|::||:                                      |:|:..::.:
Zfish   725 VVN-------SKYAFLLESTMNEYHRSLNCNLTQIGGLLDTKGYGIGMPLGSPFRDELSLAVLQL 782

  Fly   541 RSVGLLSVWSR--WELSESYLRNEQSFQVLGTMELYAIFLMVLVGLIVGLLVFILELV 596
            :....|.:..|  ||..:.....:...:.||...:..||::::.|||:.:.|.::|.|
Zfish   783 QENNRLEILKRRWWEGGKCPKEEDHRAKGLGMENIGGIFVVLICGLIIAVFVAVMEFV 840

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7e	NP_001138176.1	PBPb	218..>313	CDD:214497	23/112 (21%)
grik5	NP_001315085.1	PBP1_iGluR_Kainate_KA1_2	38..412	CDD:107389	36/185 (19%)
		ANF_receptor	55..392	CDD:279440	30/154 (19%)
		Periplasmic_Binding_Protein_Type_1	<313..383	CDD:299141	14/85 (16%)
		Periplasmic_Binding_Protein_Type_2	427..797	CDD:304360	70/453 (15%)
		Lig_chan	558..828	CDD:278489	45/320 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591763
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840