DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir7e and GluRIB

DIOPT Version :9

Sequence 1:	NP_001138176.1	Gene:	Ir7e / 7354417	FlyBaseID:	FBgn0259189	Length:	608	Species:	Drosophila melanogaster
Sequence 2:	NP_001261621.2	Gene:	GluRIB / 44484	FlyBaseID:	FBgn0264000	Length:	1182	Species:	Drosophila melanogaster

Alignment Length:	259	Identity:	57/259 - (22%)
Similarity:	98/259 - (37%)	Gaps:	48/259 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   360 FWLNLELVFVGMPLLECPRSHTARLYCVMLMMYTLIIRTIYQGLLYHLIRTHQLNRWPQTIESLV 424
            ||.:| ..|:.......|||.:.|:.......:|||:.:.|...|...:          |:|.:|
  Fly   743 FWFSL-AAFMQQGCDLSPRSVSGRIAAASWFFFTLILISSYTANLAAFL----------TVERMV 796

  Fly   425 QKNFTVVLTPIVQEVLDEIPSVQHMRFRLLEANSELDPLYFLEANHQL----------RQHVTAS 479
                    |||...  :::.....:::..|...|..|  :|..:...|          |:||...
  Fly   797 --------TPINSP--EDLAMQTEVQYGTLLHGSTWD--FFRRSQIGLHNKMWEYMNSRKHVFVP 849

  Fly   480 ALDIFIHFNRLSADKVHQRGEQGSGAHFEIVPEDIISMQLTMYLAKHSF---------LIDQLNE 535
            ..|..|...|.|..|.....|.....:.. ..|...:|::...|....|         |.|.:|.
  Fly   850 TYDEGIKRVRNSKGKYALLVESPKNEYVN-AREPCDTMKVGRNLDTKGFGIATPLGSALKDPINL 913

  Fly   536 EIMWMRSVG-LLSVWSRW--ELSE--SYLRNEQSFQVLGTMELYAIFLMVLVGLIVGLLVFILE 594
            .::.::..| |:.:.::|  |.:|  ::...|.|...|....:..||.:::.||:|.:.|.|||
  Fly   914 AVLTLKENGELIKLRNKWWYEKAECSTHKDGETSHSELSLSNVAGIFYILIGGLLVSVFVAILE 977

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir7e	NP_001138176.1	PBPb	218..>313	CDD:214497
GluRIB	NP_001261621.2	PBP1_iGluR_AMPA	43..478	CDD:107375
		ANF_receptor	55..461	CDD:279440
		PBP2_iGluR_AMPA	497..938	CDD:270433	44/218 (20%)
		Lig_chan	632..967	CDD:278489	50/247 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462550
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740