DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir7e and Ir93a

DIOPT Version :9

Sequence 1:	NP_001138176.1	Gene:	Ir7e / 7354417	FlyBaseID:	FBgn0259189	Length:	608	Species:	Drosophila melanogaster
Sequence 2:	NP_650924.3	Gene:	Ir93a / 42471	FlyBaseID:	FBgn0259215	Length:	868	Species:	Drosophila melanogaster

Alignment Length:	460	Identity:	82/460 - (17%)
Similarity:	166/460 - (36%)	Gaps:	106/460 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   220 PPFLTLDEDQEEVLRVNGGYEGRLLLALAEKMNFTIAVRKVHVNMRDEALE-MLRRDEVDLTLGG 283
            ||:..|.::...|:..:.|....::..|:..:||:..:.:......:::|. ....:|.|..:|.
  Fly   443 PPWQILTKNSNGVIVEHKGIVMEIVKELSRALNFSYYLHEASAWKEEDSLSTSAGGNESDELVGS 507

  Fly   284 I--------------RQTVARGMVAT------SSHNYHQ---TREVFGVLASSYELSSFDILFYP 325
            :              .|.....:.||      ...||.|   .::...:.....|:|...:...|
  Fly   508 MTFRIPYRVVEMVQGNQFFIAAVAATVEDPDQKPFNYTQPISVQKYSFITRKPDEVSRIYLFTAP 572

  Fly   326 YRLQIWMGILGVVALSALIQLIVGRM--LRE-------RMGSRFWLNLELVFVGMPLLE-----C 376
            :.::.|..::|::.|:|.....:.|:  |:|       .:.|.||      ::...||:     .
  Fly   573 FTVETWFCLMGIILLTAPTLYAINRLAPLKEMRIVGLSTVKSCFW------YIFGALLQQGGMYL 631

  Fly   377 PRSHTARLYCVMLMMYTLIIRTIYQGLLYHLIRTHQLNRWPQTIESLVQKNFTVVLT-PIVQEVL 440
            |.:.:.||......:..:::.|.|.|                        |....|| |..|..:
  Fly   632 PTADSGRLVVGFWWIVVIVLVTTYCG------------------------NLVAFLTFPKFQPGV 672

  Fly   441 DEIPSVQHMR-------------FRLLEANSELDPLYFLEANHQLRQHVTASA----LDIFIHFN 488
            |.:..::..:             .|.:::.:..|..::||     |..:..||    ::......
  Fly   673 DYLNQLEDHKDIVQYGLRNGTFFERYVQSTTREDFKHYLE-----RAKIYGSAQEEDIEAVKRGE 732

  Fly   489 RLSAD-------KVHQRGEQGSGAHFEIVPEDIISMQLTMYLAKHSFLIDQLNEEIMWMRSVGLL 546
            |::.|       .|.:..|:....||.:..|..:..|:.|.:...|..:..:|..|..|..:|.:
  Fly   733 RINIDWRINLQLIVQRHFEREKECHFALGRESFVDEQIAMIVPAQSAYLHLVNRHIKSMFRMGFI 797

  Fly   547 SVWSRWELSESYLRNEQSFQ------VLGTMELYAIFLMVLVGLIVGLLVFILEL--VSMRSIYL 603
            ..|.:..|..:...|.:|.|      .:...::...||::|:|..:.||:...|.  ...|:...
  Fly   798 ERWHQMNLPSAGKCNGKSAQRQVTNHKVNMDDMQGCFLVLLLGFTLALLIVCGEFWYRRFRASRK 862

  Fly   604 RKLFT 608
            |:.||
  Fly   863 RRQFT 867

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir7e	NP_001138176.1	PBPb	218..>313	CDD:214497	18/116 (16%)
Ir93a	NP_650924.3	Periplasmic_Binding_Protein_Type_2	429..>697	CDD:328725	45/283 (16%)
Ir93a	NP_650924.3	Lig_chan	576..836	CDD:306551	51/294 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462908
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840