Protein Alignment Ir7e and GluRIIE

DIOPT Version :10

• Sequence 1: NP_001138176.1
• Gene: Ir7e / 7354417
• FlyBaseID: FBgn0259189
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: NP_001036733.1
• Gene: GluRIIE / 318623
• FlyBaseID: FBgn0051201
• Length: 897
• Species: Drosophila melanogaster
• Alignment Length: 648
• Identity: 125/648 - (19%)
• Similarity: 214/648 - (33%)
• Gaps: 225/648 - (34%)

  Fly    67 FREWGLAPLQI------------VNVLRGVPWHPVP---GRRHFNVIFTDSFAAFEEIRMEYYSR 116
            ||. |..|:.:            ...|:.:|:.|:|   .:|..:|  .|..::|
  Fly   295 FRN-GSCPITVEMALTYDAVQLFAQTLKNLPFKPMPQNCSQRTESV--RDDGSSF---------- 346

  Fly   117 EYNYNEHYFIFLQARDRLLQGEMRLIFDYCWRYRLIHCSIQVQKS-NGDILFYSYYPFG--EHGC 178
                 ::|...|:..||||.|.             |:....|:|. :.|::  ...|.|  :.|.
  Fly   347 -----KNYMRTLRLTDRLLTGP-------------IYFEGNVRKGYHLDVI--ELQPSGIVKVGT 391

  Fly   179 SDMEPQLINRYNGSMLVEPDLFPRKLRN--FFGCPLRCALWDVP--PFLTLDEDQEEVLRVNGGY 239
            .|.:.|...:.......:.|.....|.|  |.      .|..||  |:..|.|..:: |..|..|
  Fly   392 WDEDRQYRPQRLAPTTAQFDSVDNSLANKTFI------ILLSVPNKPYAQLVETYKQ-LEGNSQY 449

  Fly   240 EG---RLLLALAEKM--NFTIA-------------------VRKVHVNMRDEALEML-----RRD 275
            ||   .|:..||:|:  |||..                   :|::.....|.|:..|     |..
  Fly   450 EGYGVDLIKELADKLGFNFTFVNGGNDYGSYNKSTNESTGMLREIMTGRADLAITDLTITSEREQ 514

  Fly   276 EVDLTLG----GIRQTVARGMVATSSHNYHQTREVFGVLASSYELSSFDILFYPYRLQIW----M 332
            .:|.|:.    ||.....:...||.                  ||.:|   ..|:..::|    .
  Fly   515 ALDFTIPFMNLGIAILYLKPQKATP------------------ELFTF---MDPFSEEVWWFLGF 558

  Fly   333 GILGVVALSALIQLIVGRML-------------RERMGSRFWLNLELVFVGMPLLE-----CPRS 379
            ..|||    :|...|:||:.             .|.:.::|.|...:.|....||:     .|::
  Fly   559 SFLGV----SLSFFILGRLSPSEWDNPYPCIEEPEELENQFTLGNSIWFTTGALLQQGSEIGPKA 619

  Fly   380 HTARLYCVMLMMYTLIIRTIYQGLLYHLIRTHQLNRWPQTIESLVQKNFTVVLTPIVQEVLDEIP 444
            .:.|........:|||:.:.|...|...:...:    ||   ||:..         |.::.|...
  Fly   620 LSTRTVASFWWFFTLIVVSSYTANLAAFLTIEK----PQ---SLINS---------VDDLADNKD 668

  Fly   445 SVQH-----------------MRFRLLEANSELDPLYFLEANHQLRQHVTASALDIF------IH 486
            .|.:                 .|::.:......:|.|..|.|.:....|..:....|      |.
  Fly   669 GVVYGAKKTGSTRNFFMTSAEERYKKMNKFMSENPQYLTEDNMEGVNRVKTNTHYAFLMESTSIE 733

  Fly   487 FNRLSADKVHQRG----EQGSGAHFEIVPEDIISMQLTMYLAKHSFLIDQLNEEIMWMRSVGLL- 546
            :|......:.:.|    |:|.|          |:|:...   .|.   .:.|..::.::..|:|
  Fly   734 YNTKRECNLKKIGDALDEKGYG----------IAMRKDW---PHR---GKFNNALLELQEQGVLE 782

  Fly   547 SVWSRWELSESYLRNEQSFQVLGTME------------LYAIFLMVLVG----LIVGLLVFIL 593
            .:.::|       .||....:..|.|            |..:|.::|||    |:.|::.::|
  Fly   783 KMKNKW-------WNEVGTGICATKEDAPDATPLDMNNLEGVFFVLLVGSCCALLYGIISWVL 838

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7e	NP_001138176.1	Periplasmic_Binding_Protein_Type_2	218..>313	CDD:473866	28/129 (22%)
GluRIIE	NP_001036733.1	PBP1_iGluR_Kainate	40..402	CDD:380605	28/139 (20%)
		PBP2_iGluR_Kainate	419..790	CDD:270432	83/441 (19%)
		Lig_chan	551..824	CDD:459656	55/315 (17%)