Protein Alignment Ir7e and GluRIIE

DIOPT Version :9

• Sequence 1: NP_001138176.1
• Gene: Ir7e / 7354417
• FlyBaseID: FBgn0259189
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: NP_001036733.1
• Gene: GluRIIE / 318623
• FlyBaseID: FBgn0051201
• Length: 897
• Species: Drosophila melanogaster
• Alignment Length: 651
• Identity: 126/651 - (19%)
• Similarity: 214/651 - (32%)
• Gaps: 231/651 - (35%)

  Fly    67 FREWGLAPLQI------------VNVLRGVPWHPVP---GRRHFNVIFTDSFAAFEEIRMEYYSR 116
            ||. |..|:.:            ...|:.:|:.|:|   .:|..:|  .|..::|
  Fly   295 FRN-GSCPITVEMALTYDAVQLFAQTLKNLPFKPMPQNCSQRTESV--RDDGSSF---------- 346

  Fly   117 EYNYNEHYFIFLQARDRLLQGEMRLIFDYCWRYRLIHCSIQVQKS-NGDILFYSYYPFG--EHGC 178
                 ::|...|:..||||.|.             |:....|:|. :.|::  ...|.|  :.|.
  Fly   347 -----KNYMRTLRLTDRLLTGP-------------IYFEGNVRKGYHLDVI--ELQPSGIVKVGT 391

  Fly   179 SDMEPQLINRYNGSMLVEPDLFPRKLRN--FFGCPLRCALWDVP--PFLTLDEDQEEVLRVNGGY 239
            .|.:.|...:.......:.|.....|.|  |.      .|..||  |:..|.|..:: |..|..|
  Fly   392 WDEDRQYRPQRLAPTTAQFDSVDNSLANKTFI------ILLSVPNKPYAQLVETYKQ-LEGNSQY 449

  Fly   240 EG---RLLLALAEKM--NFTIA-------------------VRKVHVNMRDEALEML-----RRD 275
            ||   .|:..||:|:  |||..                   :|::.....|.|:..|     |..
  Fly   450 EGYGVDLIKELADKLGFNFTFVNGGNDYGSYNKSTNESTGMLREIMTGRADLAITDLTITSEREQ 514

  Fly   276 EVDLTLG----GIRQTVARGMVATSSHNYHQTREVFGVLASSYELSSFDILFYPYRLQIW----M 332
            .:|.|:.    ||.....:...||.                  ||.:|   ..|:..::|    .
  Fly   515 ALDFTIPFMNLGIAILYLKPQKATP------------------ELFTF---MDPFSEEVWWFLGF 558

  Fly   333 GILGVVALSALIQLIVGRML-------------RERMGSRFWLNLELVFVGMPLLE-----CPRS 379
            ..|||    :|...|:||:.             .|.:.::|.|...:.|....||:     .|::
  Fly   559 SFLGV----SLSFFILGRLSPSEWDNPYPCIEEPEELENQFTLGNSIWFTTGALLQQGSEIGPKA 619

  Fly   380 HTARLYCVMLMMYTLIIRTIYQGLLYHLIRTHQLNRWPQTIE---SLVQKNFTVVLTPIVQEVLD 441
            .:.|........:|||:.:.|...|...:          |||   ||:..         |.::.|
  Fly   620 LSTRTVASFWWFFTLIVVSSYTANLAAFL----------TIEKPQSLINS---------VDDLAD 665

  Fly   442 EIPSVQH-----------------MRFRLLEANSELDPLYFLEANHQLRQHVTASALDIF----- 484
            ....|.:                 .|::.:......:|.|..|.|.:....|..:....|
  Fly   666 NKDGVVYGAKKTGSTRNFFMTSAEERYKKMNKFMSENPQYLTEDNMEGVNRVKTNTHYAFLMEST 730

  Fly   485 -IHFNRLSADKVHQRG----EQGSGAHFEIVPEDIISMQLTMYLAKHSFLIDQLNEEIMWMRSVG 544
             |.:|......:.:.|    |:|.|          |:|:...   .|.   .:.|..::.::..|
  Fly   731 SIEYNTKRECNLKKIGDALDEKGYG----------IAMRKDW---PHR---GKFNNALLELQEQG 779

  Fly   545 LL-SVWSRWELSESYLRNEQSFQVLGTME------------LYAIFLMVLVG----LIVGLLVFI 592
            :| .:.::|       .||....:..|.|            |..:|.::|||    |:.|::.::
  Fly   780 VLEKMKNKW-------WNEVGTGICATKEDAPDATPLDMNNLEGVFFVLLVGSCCALLYGIISWV 837

  Fly   593 L 593
            |
  Fly   838 L 838

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7e	NP_001138176.1	PBPb	218..>313	CDD:214497	28/129 (22%)
GluRIIE	NP_001036733.1	PBP1_iGluR_Kainate	42..396	CDD:107377	27/133 (20%)
		ANF_receptor	51..382	CDD:279440	23/119 (19%)
		PBP2_iGluR_Kainate	419..790	CDD:270432	84/444 (19%)
		Lig_chan	551..824	CDD:278489	56/318 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462854
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740