DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir7e and Ir7g

DIOPT Version :9

Sequence 1:	NP_001138176.1	Gene:	Ir7e / 7354417	FlyBaseID:	FBgn0259189	Length:	608	Species:	Drosophila melanogaster
Sequence 2:	NP_001368933.1	Gene:	Ir7g / 31694	FlyBaseID:	FBgn0029968	Length:	607	Species:	Drosophila melanogaster

Alignment Length:	622	Identity:	186/622 - (29%)
Similarity:	323/622 - (51%)	Gaps:	42/622 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MNISALLN---SYYDLSGEQMNHINEFVARAVLHVVHHYILSVTPSLVLTLCCRSNHTCNFYNKM 62
            ||:::|||   ..|..:..|...||..||:|:...:..:...:.|:.::.|.||.....|||..:
  Fly     1 MNVTSLLNFESMKYIGAQTQAASINHHVAQALRVFIEDFYQRIAPAFIVVLSCRRPSPMNFYRNI 65

  Fly    63 MSTLFREWGLAPLQIVNVLRGVPWHPVPGRRHFNVIFTDSFAAFEEIRMEYYSREYNYNEHYFIF 127
            |..|:.......:|:|.|..|.| ..:.|.|..|::..||..|..:|.:..|:.:.:.:|:||||
  Fly    66 MQLLYESVDTMIVQLVLVELGRP-RRIAGPRTHNLLLVDSLDALLDIEIHTYTAQSDTSEYYFIF 129

  Fly   128 LQARDRLLQGEMRLIFDYCWRYRLIHCSIQVQKSNGDILFYSYYPFGEHGCSDMEPQLINRYNGS 192
            ||.||.|:..:|:.:|.||||::||:|::..|.|.|.:|.::|:|:....|:|.:|..||.:.|.
  Fly   130 LQQRDALIPHDMQGVFAYCWRHQLINCNVMTQSSGGQVLLHTYFPYAPGQCNDSQPTRINMFLGE 194

  Fly   193 MLVEPDLFPRKLRNFFGCPLRCALWDVPPFLTLDEDQEEVLRVNGGYEGRLLLALAEKMNFTIAV 257
            .....|.||.||.|..||||......|.|||.|||.|.| ||   |.|||||..|:.:|||:|..
  Fly   195 SWKHRDYFPSKLHNLNGCPLIVLARKVSPFLDLDEGQRE-LR---GLEGRLLQELSRRMNFSIQF 255

  Fly   258 RKVHVNMRD-------EALEMLRRDEV-DLTLGGIRQTVARGMVATSSHNYHQTREVFGVLASSY 314
            ..:...:::       :.|:.|.::.: .|.:|.:|:.:......|....::..|.|..:|.:::
  Fly   256 SGLQDQLKNRTTWTEKQLLQKLVQERIAHLAIGYVRKRIQYATNLTPVFPHYSNRVVGCLLLNAH 320

  Fly   315 ELSSFDILFYPYRLQIWMG-ILGVVALSALIQLIVGRMLRER-MGSRFWLNLEL--VFVGMPLLE 375
            .|:|.:|..:|::...|:. :...:::|.|      .:|..| .|.|..|.|.:  ..:|:| ::
  Fly   321 NLTSLEIWSFPFQALTWICLVFSFLSISCL------ALLHXRGAGDRLALVLAVYAASLGLP-ID 378

  Fly   376 CPRSHTARLYCVMLMMYTLIIRTIYQGLLYHLIRTHQLNRWPQTIESLVQKNFTVVLTPIVQEVL 440
            .|...:.:|.....:::.||:|::|..||:.::|.|...|.|..::.|...::..|:.....:.|
  Fly   379 PPERPSLQLLFASWLIFGLIVRSMYSALLFFILRYHLHQRLPGNLQDLTHGDYAAVMGRTTLQDL 443

  Fly   441 DEIPSVQH---MRFRLLEANSELDPLYFLEANHQLRQHVTASALDIFIHFNRLSADK-VH--QRG 499
            .|:||:|.   ::..::.:..|.:.|..|: ...||:...:..|    .|..:|.|. :|  |||
  Fly   444 REVPSLQDLLGLKSVIVTSEREEEVLRTLD-RCTLREGAGSHPL----FFGLISQDALLHLTQRG 503

  Fly   500 EQGSGAHFEIVPEDIISMQLTMYLAKHSFLIDQLNEEIMWMRSVGLLSVWSRWELSESYLRNEQS 564
            .:....|  |:|:|::..||.:||.|||.|...|:..:|.:|||||:..|:....||.|.|:...
  Fly   504 HRAGAYH--IIPQDVLEQQLAIYLQKHSHLASHLDHLVMSIRSVGLVHHWAGQMASERYFRSRFL 566

  Fly   565 FQV--LGTMELYAIFLMVLVGLIVGLLVFILELVSMR 599
            ::.  :...:|:|::::.....::.|:|||.||::.|
  Fly   567 YREKRIRQPDLWAVYILTAGLYLLSLVVFICELLASR 603

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir7e	NP_001138176.1	PBPb	218..>313	CDD:214497	31/102 (30%)
Ir7g	NP_001368933.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440208
Domainoid	1	1.000	149	1.000	Domainoid score	I9056
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25775
OrthoDB	1	1.010	-	-		D71073at33392
OrthoFinder	1	1.000	-	-		FOG0007621
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42643
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.960