Protein Alignment Ir7e and Grik3

DIOPT Version :9

• Sequence 1: NP_001138176.1
• Gene: Ir7e / 7354417
• FlyBaseID: FBgn0259189
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: NP_001106187.1
• Gene: Grik3 / 298521
• RGDID: 71027
• Length: 919
• Species: Rattus norvegicus
• Alignment Length: 655
• Identity: 127/655 - (19%)
• Similarity: 218/655 - (33%)
• Gaps: 220/655 - (33%)

  Fly    28 AVLHVVHHYILSV----TPSL-VLTLCCRSNHTCNFYNKMMSTLFR-EW-GLAPLQIVNVLRGV- 84
            |:|:...| |:||    .|.: |.:|.|..:....|..:.|:.:.. :| ||....:.|...|:
  Rat   324 ALLYDAVH-IVSVCYQRAPQMTVNSLQCHRHKAWRFGGRFMNFIKEAQWEGLTGRIVFNKTSGLR 387

  Fly    85 -------------------PWHPVPG--------RRHFNVIFTDSFAAFEEIRMEYYSREYNYNE 122
                               .|.|..|        .|..||  |||......|.....       |
  Rat   388 TDFDLDIISLKEDGLEKVGVWSPADGLNITEVAKGRGPNV--TDSLTNRSLIVTTLL-------E 443

  Fly   123 HYFIFLQARDRLLQGEMRLIFD-YCWRYRLIHCSIQVQKSNGDILFYSY----YPFGEHGCSDME 182
            ..|:..:..||.|.|..|  |: ||         |.:.|....||.:||    ...|::|..|.:
  Rat   444 EPFVMFRKSDRTLYGNDR--FEGYC---------IDLLKELAHILGFSYEIRLVEDGKYGAQDDK 497

  Fly   183 PQLINRYNGSMLVEPDLFPRKLRNFFGCPLRCALWDVPPFLTLDEDQEEVLRVNGGYEGRLLLAL 247
            .|    :|| |:.|                           .:|...:              ||:
  Rat   498 GQ----WNG-MVKE---------------------------LIDHKAD--------------LAV 516

  Fly   248 AEKMNFTIAVRKVHVNMRDEALEMLRRDEVDLTLGGIRQTVARGMVATSSHNYHQTR-EVFGVLA 311
            |.   .||    .||  |::|::.   .:..:|||          |:......:.|. .||..|
  Rat   517 AP---LTI----THV--REKAIDF---SKPFMTLG----------VSILYRKPNGTNPSVFSFL- 558

  Fly   312 SSYELSSFDILFYPYRLQIWMGI-LGVVALSALIQLIV---------------GRMLRER---MG 357
                        .|....|||.: |..:.:|.::.:|.               |..:.|.   :.
  Rat   559 ------------NPLSPDIWMYVLLAYLGVSCVLFVIARFSPYEWYDAHPCNPGSEVVENNFTLL 611

  Fly   358 SRFWLNL-ELVFVGMPLLECPRSHTARLYCVMLMMYTLIIRTIYQGLLYHLIRTHQLNRWPQTIE 421
            :.||..: .|:..|..|:  |::.:.|:...:...:||||.:.|...|...:...::.....:.:
  Rat   612 NSFWFGMGSLMQQGSELM--PKALSTRIIGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSAD 674

  Fly   422 SLVQKNFTVVLTPIVQEVLDEIPSVQHMR------FRLLEANSELDPLYFLEANHQ-LRQHVTAS 479
            .|.::      |.|....:.:..::...:      |..:.|.....|...::.|.: :::.:||
  Rat   675 DLAKQ------TKIEYGAVKDGATMTFFKKSKISTFEKMWAFMSSKPSALVKNNEEGIQRTLTA- 732

  Fly   480 ALDIFIHFNRLSADKVHQRG-----------EQGSGAHFEIVPEDIISMQLTMYLAKHSFLIDQL 533
              |..:.....:.:.:.||.           .:|.|         |.:...:.|..|.:..|.||
  Rat   733 --DYALLMESTTIEYITQRNCNLTQIGGLIDSKGYG---------IGTPMGSPYRDKITIAILQL 786

  Fly   534 NEE----IM---WMRSVGLLSVWSRWELSESYLRNEQSFQVLGTMELYAIFLMVLVGLIVGLLVF 591
            .||    ||   |.|..|...            ...:....||..::..||:::..||::.:||.
  Rat   787 QEEDKLHIMKEKWWRGSGCPE------------EENKEASALGIQKIGGIFIVLAAGLVLSVLVA 839

  Fly   592 ILELV 596
            :.|.:
  Rat   840 VGEFI 844

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7e	NP_001138176.1	PBPb	218..>313	CDD:214497	18/95 (19%)
Grik3	NP_001106187.1	PBP1_iGluR_Kainate_GluR5_7	34..417	CDD:107388	20/93 (22%)
		ANF_receptor	55..398	CDD:279440	17/74 (23%)
		PBP2_iGluR_Kainate_GluR7	433..801	CDD:270441	90/486 (19%)
		Lig_chan	564..832	CDD:278489	52/299 (17%)
		Glutamate binding	690..692		0/1 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350124
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740