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Protein Alignment Ir7e and GRIA2

DIOPT Version :9

Sequence 1:	NP_001138176.1	Gene:	Ir7e / 7354417	FlyBaseID:	FBgn0259189	Length:	608	Species:	Drosophila melanogaster
Sequence 2:	NP_000817.5	Gene:	GRIA2 / 2891	HGNCID:	4572	Length:	883	Species:	Homo sapiens

Alignment Length:	439	Identity:	78/439 - (17%)
Similarity:	162/439 - (36%)	Gaps:	94/439 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   221 PFLTLDEDQEEVLRVNGGYEGRLLLALAE-------KMNFTI------AVRKVHVNMRDEALEML 272
            |::.:.:: .|:|..|..|||..:...||       |...||      ..|.....:.:..:..|
Human   425 PYVMMKKN-HEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGEL 488

  Fly   273 RRDEVDLTLGGIRQTVARGMVATSSHNYHQTREVFGVLASSYELSSFDILFY--PYRLQIWMGIL 335
            ...:.|:.:..:..|:.|..|...|..:....  ..::....:.|...:..:  |...:|||.|:
Human   489 VYGKADIAIAPLTITLVREEVIDFSKPFMSLG--ISIMIKKPQKSKPGVFSFLDPLAYEIWMCIV 551

  Fly   336 GVVALSALIQLIVGRML------------RERMGSR----------FWLNLELVFVGMPLLECPR 378
            ......:::..:|.|..            ||...|.          .|.:|. .|:.......||
Human   552 FAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLG-AFMQQGCDISPR 615

  Fly   379 SHTARLYCVMLMMYTLIIRTIYQGLLYHLIRTHQLNRWPQTIESLVQKNFTVVLTPIVQEVLDEI 443
            |.:.|:...:...:||||.:.|...|...:          |:|.:|        :||  |..:::
Human   616 SLSGRIVGGVWWFFTLIIISSYTANLAAFL----------TVERMV--------SPI--ESAEDL 660

  Fly   444 PSVQHMRFRLLEANSELDPLYFLEAN----HQLRQHVTASALDIFIHFNRLSADKVHQ-RGEQGS 503
            .....:.:..|::.|..:  :|..:.    .::..::.::...:|:   |.:|:.|.: |..:|.
Human   661 SKQTEIAYGTLDSGSTKE--FFRRSKIAVFDKMWTYMRSAEPSVFV---RTTAEGVARVRKSKGK 720

  Fly   504 GAH-FEIVPEDIISMQL---TMYLA-------------KHSFLIDQLNEEIMWMRSVGLL-SVWS 550
            .|: .|....:.|..:.   ||.:.             |.|.|...:|..::.:...|:| .:.:
Human   721 YAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLSEQGVLDKLKN 785

  Fly   551 RW-----ELSESYLRNEQSFQVLGTMELYAIFLMVLVGLIVGLLVFILE 594
            :|     |.......:::....|....:..:|.:::.||.:.:||.::|
Human   786 KWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIE 834

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.