Protein Alignment Ir7e and Grik5

DIOPT Version :9

• Sequence 1: NP_001138176.1
• Gene: Ir7e / 7354417
• FlyBaseID: FBgn0259189
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: XP_006228444.1
• Gene: Grik5 / 24407
• RGDID: 2735
• Length: 980
• Species: Rattus norvegicus
• Alignment Length: 628
• Identity: 108/628 - (17%)
• Similarity: 199/628 - (31%)
• Gaps: 223/628 - (35%)

  Fly    68 REWGLAPL------------QIVNVLRGVPWHPVPGRRHFNVIFTDSFAAFEEIRMEYYSREYNY 120
            :|.|:.||            .::|.||.|.:..:.||..||                ...:..||
  Rat   325 QEIGVKPLACTSANIWPHGTSLMNYLRMVEYDGLTGRVEFN----------------SKGQRTNY 373

  Fly   121 NEHYFIFLQARDRLLQGEMRLIFDYCWRYRLIHCSIQVQKSNGDILFYSYYPFGEHGCSDMEPQL 185
            .      |:..::..||               |..|.|..||..:..         ..:.::..|
  Rat   374 T------LRILEKSRQG---------------HREIGVWYSNRTLAM---------NATTLDINL 408

  Fly   186 INRYNGSMLVEPDLF--PRKLRNFFGCPLRCALWDVPPFLTLDEDQEEVLRVNGGYEG---RLLL 245
            ........||...:.  |..:|.             |.|        :.|..|..:||   .:|.
  Rat   409 SQTLANKTLVVTTILENPYVMRR-------------PNF--------QALSGNERFEGFCVDMLR 452

  Fly   246 ALAEKMNFTIAVRKVHVNMRDEAL---------------EMLRRDEVDLTLGGIRQTVARGMVAT 295
            .|||.:.|...:|.|     ::.|               |::.|.:.||.:.....|..|..|..
  Rat   453 ELAELLRFRYRLRLV-----EDGLYGAPEPNGSWTGMVGELINRQKADLAVAAFTITAEREKVID 512

  Fly   296 SS-----------HNYHQTREVFGVLASSYELSSFDILFYPYRLQIWM-GILGVVALSALIQLIV 348
            .|           :..|..|:      ..| .|..|    |:...:|: .:|..:|:|.:: .:.
  Rat   513 FSKPFMTLGISILYRVHMGRK------PGY-FSFLD----PFSPAVWLFMLLAYLAVSCVL-FLA 565

  Fly   349 GRM-----------LRER---------MGSRFWLNL-ELVFVGMPLLECPRSHTARLYCVMLMMY 392
            .|:           ||.|         :|:..|..: ..:..|..::  ||:.:.|....:...:
  Rat   566 ARLSPYEWYNPHPCLRARPHILENQYTLGNSLWFPVGGFMQQGSEIM--PRALSTRCVSGVWWAF 628

  Fly   393 TLIIRTIYQGLLYHLIRTHQLNRWPQTIESLVQKNFTVVLTPIVQEVLDEIPSVQHMRFRLLEAN 457
            ||||.:.|...|...:...::.                  .|:  |..|::....::.:..:.|.
  Rat   629 TLIIISSYTANLAAFLTVQRME------------------VPV--ESADDLADQTNIEYGTIHAG 673

  Fly   458 SELDPLYFLEANHQLRQ----HVTASALDIFI-------------------------HFNRLSAD 493
            |.:  .:|..:.:|..|    ::.:....:|:                         :..||:.:
  Rat   674 STM--TFFQNSRYQTYQRMWNYMQSKQPSVFVKSTEEGIARVLNSRYAFLLESTMNEYHRRLNCN 736

  Fly   494 KVHQRG---EQGSGAHFEIVPEDIISMQLTMYLAKHSFLIDQLNEEIMWMRSVGLLSVWSR--WE 553
            .....|   .:|.|          |.|.|      .|...|::...|:.::....|.:..|  ||
  Rat   737 LTQIGGLLDTKGYG----------IGMPL------GSPFRDEITLAILQLQENNRLEILKRKWWE 785

  Fly   554 LSESYLRNEQSFQVLGTMELYAIFLMVLVGLIVGLLVFILELV 596
            ........:...:.||...:..||::::.|||:.:.|.::|.:
  Rat   786 GGRCPKEEDHRAKGLGMENIGGIFVVLICGLIIAVFVAVMEFI 828

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7e	NP_001138176.1	PBPb	218..>313	CDD:214497	24/123 (20%)
Grik5	XP_006228444.1	PBP1_iGluR_Kainate_KA1_2	23..401	CDD:380616	22/121 (18%)
		Periplasmic_Binding_Protein_Type_2	414..785	CDD:389745	74/448 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350159
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740