Protein Alignment Ir7e and Grin3b

DIOPT Version :9

• Sequence 1: NP_001138176.1
• Gene: Ir7e / 7354417
• FlyBaseID: FBgn0259189
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: XP_006513350.1
• Gene: Grin3b / 170483
• MGIID: 2150393
• Length: 1138
• Species: Mus musculus
• Alignment Length: 480
• Identity: 93/480 - (19%)
• Similarity: 162/480 - (33%)
• Gaps: 147/480 - (30%)

  Fly   190 NGSMLVEPDLFPRKLRNFFGCPLRCALWDVPPFLTLDEDQEEVLRVNGGYEGRLLLALAEKMNFT 254
            |||:       ||.||       ||..                     ||...||..|||.:.|.
Mouse   545 NGSV-------PRTLR-------RCCY---------------------GYCIDLLERLAEDLAFD 574

  Fly   255 IAVRKV----HVNMRDEALEMLRRDEVDLTLGGIRQTV-------ARGMVATSSHNYHQTREVFG 308
            ..:..|    :..:||.....|   ..||..|.....|       ||..|...:..:..|.  .|
Mouse   575 FELYIVGDGKYGALRDGRWTGL---VGDLLAGRAHMAVTSFSINSARSQVVDFTSPFFSTS--LG 634

  Fly   309 VLASSYELSS-FDILFYPYRLQIWMGILGVVALSALI---------------------------- 344
            ::..:.:.:| .....:|....:|:|:...:.|:||.
Mouse   635 IMVRTRDTASPIGAFMWPLHWSMWVGVFAALHLTALFLTLYEWRSPYGLTPRGRNRGTVFSYSSA 699

  Fly   345 -----QLIVGRMLRERM----GSRFWLNLELVFVGMPLLECPRSHTARLYCVMLMMYTL-IIRTI 399
                 .::.||.:..:.    ..||.:||..:|..:.|    .|:||.|..||:...|. .:..|
Mouse   700 LNLCYAILFGRTVSSKTPKCPTGRFLMNLWAIFCLLVL----SSYTANLAAVMVGDKTFEELSGI 760

  Fly   400 YQGLLYHLIRTHQLNR-WPQTIESLVQKNFTVVLTPIVQEVLDEIPSVQHMRFRLLEANSELDPL 463
            :...|:|..:..:... |..:.|:.::.:|..:...:.:.   ..|:..|....|.....:|:..
Mouse   761 HDPKLHHPSQGFRFGTVWESSAEAYIKASFPEMHAHMRRH---SAPTTPHGVAMLTSDPPKLNAF 822

  Fly   464 YFLEANHQLRQHVTASALDIFIHFNRLSAD-KVHQRGE----QGSGAHFEIVPEDIISMQLTMYL 523
            .           :..|.||..:   .:.|| |:...|:    :|.|                :.|
Mouse   823 I-----------MDKSLLDYEV---SIDADCKLLTVGKPFAIEGYG----------------IGL 857

  Fly   524 AKHSFLIDQLNEEIMWMRSVGLLSVWSRWELSESYLR----NEQSFQV-----LGTMELYAIFLM 579
            .::|.|...|:|.|...:|.|.:.:     |.:.:.:    .::.|.|     :|...|..:|::
Mouse   858 PQNSPLTSNLSEFISRYKSSGFIDL-----LHDKWYKMVPCGKRVFAVTETLQMGVYHLSGLFVL 917

  Fly   580 VLVGLIVGLLVFILELVSMRSIYLR 604
            :.:||...||..:.|.|..|.:..|
Mouse   918 LCLGLGSALLTSLGEHVFYRLVLPR 942

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7e	NP_001138176.1	PBPb	218..>313	CDD:214497	21/105 (20%)
Grin3b	XP_006513350.1	PBP1_iGluR_NMDA_NR3	141..481	CDD:380600
		PBP2_iGluR_NMDA_Nr3	494..888	CDD:270438	80/424 (19%)
		Lig_chan	656..922	CDD:365843	53/307 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846616
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740