DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir7e and gria3a

DIOPT Version :9

Sequence 1:	NP_001138176.1	Gene:	Ir7e / 7354417	FlyBaseID:	FBgn0259189	Length:	608	Species:	Drosophila melanogaster
Sequence 2:	XP_005165152.1	Gene:	gria3a / 170452	ZFINID:	ZDB-GENE-020125-5	Length:	903	Species:	Danio rerio

Alignment Length:	153	Identity:	32/153 - (20%)
Similarity:	63/153 - (41%)	Gaps:	40/153 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   390 MMYTLIIRTIYQGLLYHLIRTHQLNRWPQTI----------------ESLVQKNFTV-------V 431
            :.:.|.:|...:|.|..|:..:   :|.:.:                ||.|..|:.|       :
Zfish   128 VQFVLQMRPSLRGALLSLLAHY---KWEKFVYLYDTDRGFSILQAIMESAVMNNWQVTARSVGNI 189

  Fly   432 LTPI-VQEVLDEIPSVQHMRFRLLEA-----NSELDPLYFLEANHQLRQHVTASALDIFIHFNRL 490
            :.|: .:.:::|:...|..|| |::.     ||.|:.:.....|.:...::.|:     :.|..:
Zfish   190 VDPLEYRRIIEEMDRRQEKRF-LIDCEVERINSILEQVVIAGKNSRGYHYILAN-----LGFTNM 248

  Fly   491 SADKVHQRGEQGSGAHFEIVPED 513
            |.|||...|...:|  |:|:..|
Zfish   249 SLDKVFSGGANITG--FQIINPD 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir7e	NP_001138176.1	PBPb	218..>313	CDD:214497
gria3a	XP_005165152.1	PBP1_iGluR_AMPA_GluR3	28..399	CDD:107382	32/153 (21%)
		ANF_receptor	39..382	CDD:279440	32/153 (21%)
		PBP2_iGluR_AMPA	415..797	CDD:270433
		Lig_chan	547..810	CDD:278489
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591778
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740