Protein Alignment Ir7e and Grin2d

DIOPT Version :9

• Sequence 1: NP_001138176.1
• Gene: Ir7e / 7354417
• FlyBaseID: FBgn0259189
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: XP_036008580.1
• Gene: Grin2d / 14814
• MGIID: 95823
• Length: 1345
• Species: Mus musculus
• Alignment Length: 629
• Identity: 122/629 - (19%)
• Similarity: 205/629 - (32%)
• Gaps: 179/629 - (28%)

  Fly    66 LFREWGLAP-----LQIVN-VLRGVPWHPVPGRRHFNVIFTDSFAAFEEIRMEYYSREYNYNEHY 124
            |.|::|..|     .:..| ..||...|     |:|..|..|             :|:|::||..
Mouse   336 LLRDYGFLPELGHDCRAQNRTHRGESLH-----RYFMNITWD-------------NRDYSFNEDG 382

  Fly   125 F-------IFLQARDRLL-------QGEMRLIFDYCWRY-RLI-------HCSIQVQKSNGDILF 167
            |       :....|||..       |..:||.:....|| |.:       |.::...:....::.
Mouse   383 FLVNPSLVVISLTRDRTWEVVGSWEQQTLRLKYPLWSRYGRFLQPVDDTQHLTVATLEERPFVIV 447

  Fly   168 YSYYPFGEHGCSDMEP--QLINRYNGSMLVEPDLFPRKLRNFFGCPLRCALWDVPPFLTLDEDQE 230
            ....|.......|..|  ..:||.:.  ||.|.                   ..||    |..:.
Mouse   448 EPADPISGTCIRDSVPCRSQLNRTHS--LVAPR-------------------SPPP----DAPRP 487

  Fly   231 EVLRVNGGYEGRLLLALAEKMNFTIAVRKVHVNMRDEALE-----MLRR---DEVDLTLGGIRQT 287
            | .|...|:...:|..||..:.|:..:..|......:.::     |:..   ...|:.:|.:...
Mouse   488 E-KRCCKGFCIDILKRLAHTIGFSYDLYLVTNGKHGKKIDGVWNGMIGEVFYQRADMAIGSLTIN 551

  Fly   288 VARGMVATSSHNYHQTREVFGVLASSYELSSFDILFY----------PYRLQIWMGI----LGVV 338
            ..|..:...|..:.:|.....|..|:..:|....|.:          ||...:|:.:    |.||
Mouse   552 EERSEIVDFSVPFVETGISVMVARSNGTVSPSAFLAFAWLMPPMSPEPYSPAVWVMMFVMCLTVV 616

  Fly   339 ALSALI-----------QLIVGRM---LRERMGSRFWLNLELVFVGMPLLECPRSHTARLYCVML 389
            |::..|           .|..|:.   ....:|...||...|||.....:|.||..|:::..::.
Mouse   617 AVTVFIFEYLSPVGYNRSLATGKRPGGSTFTIGKSIWLLWALVFNNSVPVENPRGTTSKIMVLVW 681

  Fly   390 MMYTLIIRTIY-QGLLYHLIRTHQLNRWPQTIESLVQKNF-------------TVVLTPIVQEVL 440
            ..:.:|....| ..|...:|:    ..:..|:..|..:.|             ||......:.:.
Mouse   682 AFFAVIFLASYTANLAAFMIQ----EEYVDTVSGLSDRKFQRPQEQYPPLKFGTVPNGSTEKNIR 742

  Fly   441 DEIPSVQHMRFRLLEANSELDPLYFLEANHQLRQHVTASALDIFIH----FNRLS-ADKVHQRGE 500
            ...|.:.....|..:...|       ||..||:    |..||.||:    .|.:: .|:..:...
Mouse   743 SNYPDMHSYMVRYNQPRVE-------EALTQLK----AGKLDAFIYDAAVLNYMARKDEGCKLVT 796

  Fly   501 QGSGAHFEIVPEDI-----------ISMQLTMYLAKHSFLIDQLNEEIMWMRSVGLLSVWSRWEL 554
            .|||..|......|           |.:.|..:|....  |:.|  |.:|:
Mouse   797 IGSGKVFATTGYGIALHKGSRWKRPIDLALLQFLGDDE--IEML--ERLWL-------------- 843

  Fly   555 SESYLRNEQSFQVLGTM----ELYAIFLMVLVGLIVGLLVFILE 594
              |.:.:....:|:.:.    .:..:|.|:||.:.:.||||..|
Mouse   844 --SGICHNDKIEVMSSKLDIDNMAGVFYMLLVAMGLSLLVFAWE 885

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7e	NP_001138176.1	PBPb	218..>313	CDD:214497	18/102 (18%)
Grin2d	XP_036008580.1	Periplasmic_Binding_Protein_type1	<156..415	CDD:415822	23/96 (24%)
		PBP2_iGluR_NMDA_Nr2	432..849	CDD:270436	86/477 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846595
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740