Protein Alignment Ir7e and Gria2

DIOPT Version :10

• Sequence 1: NP_001138176.1
• Gene: Ir7e / 7354417
• FlyBaseID: FBgn0259189
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: NP_001344853.2
• Gene: Gria2 / 14800
• MGIID: 95809
• Length: 901
• Species: Mus musculus
• Alignment Length: 310
• Identity: 60/310 - (19%)
• Similarity: 105/310 - (33%)
• Gaps: 84/310 - (27%)

  Fly     8 HVKVVLRR-LPKYMTEHEVLEQISPLPEEVIGTYFHPANFSFDR--CAYATLTVNFSEYCDSMME 69
            |::.:.|| :|  :.:.|:....:..|.|:.|.    ..|:.||  |.        |:..||::.
Mouse    24 HLQTLHRRSMP--VDDRELRSMPAAQPSELPGL----MRFNADRNSCV--------SDSSDSVIS 74

  Fly    70 FERRFDGYIF----VDSRG---NDSAAVVEAASNQNFAKC-------DRNRMKEDTRVGAILTD- 119
            .....||.::    :...|   :..|.:.....:.|  .|       ||:.:.:|.....:|.|
Mouse    75 SGSDSDGQVYKVVLLGEHGVGKSSLARIFGGVEDSN--DCEETGNTYDRSLVVDDEETSILLYDI 137

  Fly   120 ------KYYLDFCKKLEEERAIPILTLEQ-----------QIRKLNQPDDARTQIDKMETPLVKY 167
                  ::..|.|.::.:...|.....::           |:|:..|.::         .|::.
Mouse   138 WEQDNSQWLQDQCMRMGDAYIIVYSVTDKSSFEKASELRIQLRRARQSEN---------IPIIL- 192

  Fly   168 FFEKETGKRRD-YDARRQRRDEKRAEKRDKVDKF-----EKHKNVLDILMKPSVPMASTSATTSK 226
                 .|.:.| ..:|....||..|.......||     ..|.||.|:.      .........:
Mouse   193 -----VGNKSDLVRSREVSMDEGSACAVVFDCKFIETSASLHHNVRDLF------EGIVRQIRLR 246

  Fly   227 KDLKKEKPMTEKEKERWEKQDAKRKE---RNMIRKQK---FLDEKKKKHE 270
            ||.|:|........:|.|....|.|.   |.:.||.|   |..:.|..|:
Mouse   247 KDSKEENARRMANCKRRESISKKAKRFLGRMVARKNKKMAFRQKSKSCHD 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7e	NP_001138176.1	Periplasmic_Binding_Protein_Type_2	218..>313	CDD:473866	15/59 (25%)
Gria2	NP_001344853.2	PBP1_iGluR_AMPA_GluR2	28..398	CDD:380612	59/306 (19%)
		PBP2_iGluR_AMPA	413..794	CDD:270433