Protein Alignment Ir7e and Gria2

DIOPT Version :9

• Sequence 1: NP_001138176.1
• Gene: Ir7e / 7354417
• FlyBaseID: FBgn0259189
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: NP_001344853.2
• Gene: Gria2 / 14800
• MGIID: 95809
• Length: 901
• Species: Mus musculus
• Alignment Length: 439
• Identity: 78/439 - (17%)
• Similarity: 162/439 - (36%)
• Gaps: 94/439 - (21%)

  Fly   221 PFLTLDEDQEEVLRVNGGYEGRLLLALAE-------KMNFTI------AVRKVHVNMRDEALEML 272
            |::.:.:: .|:|..|..|||..:...||       |...||      ..|.....:.:..:..|
Mouse   425 PYVMMKKN-HEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGEL 488

  Fly   273 RRDEVDLTLGGIRQTVARGMVATSSHNYHQTREVFGVLASSYELSSFDILFY--PYRLQIWMGIL 335
            ...:.|:.:..:..|:.|..|...|..:....  ..::....:.|...:..:  |...:|||.|:
Mouse   489 VYGKADIAIAPLTITLVREEVIDFSKPFMSLG--ISIMIKKPQKSKPGVFSFLDPLAYEIWMCIV 551

  Fly   336 GVVALSALIQLIVGRML------------RERMGSR----------FWLNLELVFVGMPLLECPR 378
            ......:::..:|.|..            ||...|.          .|.:|. .|:.......||
Mouse   552 FAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLG-AFMQQGCDISPR 615

  Fly   379 SHTARLYCVMLMMYTLIIRTIYQGLLYHLIRTHQLNRWPQTIESLVQKNFTVVLTPIVQEVLDEI 443
            |.:.|:...:...:||||.:.|...|...:          |:|.:|        :||  |..:::
Mouse   616 SLSGRIVGGVWWFFTLIIISSYTANLAAFL----------TVERMV--------SPI--ESAEDL 660

  Fly   444 PSVQHMRFRLLEANSELDPLYFLEAN----HQLRQHVTASALDIFIHFNRLSADKVHQ-RGEQGS 503
            .....:.:..|::.|..:  :|..:.    .::..::.::...:|:   |.:|:.|.: |..:|.
Mouse   661 SKQTEIAYGTLDSGSTKE--FFRRSKIAVFDKMWTYMRSAEPSVFV---RTTAEGVARVRKSKGK 720

  Fly   504 GAH-FEIVPEDIISMQL---TMYLA-------------KHSFLIDQLNEEIMWMRSVGLL-SVWS 550
            .|: .|....:.|..:.   ||.:.             |.|.|...:|..::.:...|:| .:.:
Mouse   721 YAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLSEQGVLDKLKN 785

  Fly   551 RW-----ELSESYLRNEQSFQVLGTMELYAIFLMVLVGLIVGLLVFILE 594
            :|     |.......:::....|....:..:|.:::.||.:.:||.::|
Mouse   786 KWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIE 834

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7e	NP_001138176.1	PBPb	218..>313	CDD:214497	19/104 (18%)
Gria2	NP_001344853.2	PBP1_iGluR_AMPA_GluR2	28..398	CDD:380612
		PBP2_iGluR_AMPA	413..794	CDD:270433	70/397 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846637
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740