Protein Alignment Ir7e and GRIN3B

DIOPT Version :9

• Sequence 1: NP_001138176.1
• Gene: Ir7e / 7354417
• FlyBaseID: FBgn0259189
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: NP_619635.1
• Gene: GRIN3B / 116444
• HGNCID: 16768
• Length: 1043
• Species: Homo sapiens
• Alignment Length: 198
• Identity: 38/198 - (19%)
• Similarity: 68/198 - (34%)
• Gaps: 53/198 - (26%)

  Fly   278 DLTLGGIRQTV-------ARGMVATSSHNYHQTREVFGVLASSYELSS-FDILFYPYRLQIWMGI 334
            ||..|.....|       ||..|...:..:..|.  .|::..:.:.:| .....:|.....|:|:
Human   519 DLLAGRAHMAVTSFSINSARSQVVDFTSPFFSTS--LGIMVRARDTASPIGAFMWPLHWSTWLGV 581

  Fly   335 LGVVALSAL-----------------------------IQLIVGRMLRERMGS--------RFWL 362
            ...:.|:||                             :.|....:.|..:.|        |..:
Human   582 FAALHLTALFLTVYEWRSPYGLTPRGRNRSTVFSYSSALNLCYAILFRRTVSSKTPKCPTGRLLM 646

  Fly   363 NLELVFVGMPLLECPRSHTARLYCVMLMMYTL-IIRTIYQGLLYHLIRTHQLNR-WPQTIESLVQ 425
            ||..:|..:.|    .|:||.|..||:...|. .:..|:...|:|..:..:... |..:.|:.::
Human   647 NLWAIFCLLVL----SSYTANLAAVMVGDKTFEELSGIHDPKLHHPAQGFRFGTVWESSAEAYIK 707

  Fly   426 KNF 428
            |:|
Human   708 KSF 710

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7e	NP_001138176.1	PBPb	218..>313	CDD:214497	9/41 (22%)
GRIN3B	NP_619635.1	PBP1_iGluR_NMDA_NR3	19..405	CDD:107372
		PBP2_iGluR_NMDA_Nr3	415..808	CDD:270438	38/198 (19%)
		Lig_chan	576..842	CDD:278489	27/139 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156193
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.830