Protein Alignment Ir7e and Grik4

DIOPT Version :9

• Sequence 1: NP_001138176.1
• Gene: Ir7e / 7354417
• FlyBaseID: FBgn0259189
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: NP_780690.2
• Gene: Grik4 / 110637
• MGIID: 95817
• Length: 956
• Species: Mus musculus
• Alignment Length: 449
• Identity: 81/449 - (18%)
• Similarity: 160/449 - (35%)
• Gaps: 120/449 - (26%)

  Fly   221 PFLTLDEDQEEVLRVNGGYEG---RLLLALAEKMNFTIAVRKV--------HVNMRDEAL--EML 272
            |:|.|..:.:| :..|..|||   .:|..|||.:.|...:|.|        ..|.....:  |::
Mouse   427 PYLMLKGNHQE-MEGNDRYEGFCVDMLKELAEILRFNYKIRLVGDGVYGVPEANGTWTGMVGELI 490

  Fly   273 RRDEVDLTLGGIRQTVARGMVATSS-----------HNYHQTREVFGVLASSYELSSFDILFYPY 326
            .| :.||.:.|:..|..|..|...|           :..|..|.      ..| .|..|    |:
Mouse   491 AR-KADLAVAGLTITAEREKVIDFSKPFMTLGISILYRVHMGRR------PGY-FSFLD----PF 543

  Fly   327 RLQIWM-GILGVVALSALIQLIV---------------GR----MLRERMGSRFWLNLELVFVGM 371
            ...:|: .:|..:|:|.::.|:.               ||    :.:..:|:..|..:. .|:..
Mouse   544 SPGVWLFMLLAYLAVSCVLFLVARLTPYEWYSPHPCAQGRCNLLVNQYSLGNSLWFPVG-GFMQQ 607

  Fly   372 PLLECPRSHTARLYCVMLMMYTLIIRTIYQGLLYHLIRTHQLNRWPQTIESLVQKNFTVVLTPIV 436
            .....||:.:.|....:...:||||.:.|...|...:...::.                  .||
Mouse   608 GSTIAPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRME------------------VPI- 653

  Fly   437 QEVLDEIPSVQHMRFRLLEANSELDPLYFLEANHQLRQ----HVTASALDIFIHFNRLSADKVHQ 497
             |.:|::.....:.:..:...|.:  .:|..:.:|..|    ::.:....:|:           :
Mouse   654 -ESVDDLADQTAIEYGTIHGGSSM--TFFQNSRYQTYQRMWNYMYSKQPSVFV-----------K 704

  Fly   498 RGEQG----SGAHFEIVPEDII-------SMQLTMY------------LAKHSFLIDQLNEEIMW 539
            ..|:|    ..:::..:.|..:       :..||..            :...|...|:.:..|:.
Mouse   705 STEEGIARVLNSNYAFLLESTMNEYYRQRNCNLTQIGGLLDTKGYGIGMPVGSVFRDEFDLAILQ 769

  Fly   540 MRSVGLLSVWSR--WELSESYLRNEQSFQVLGTMELYAIFLMVLVGLIVGLLVFILELV 596
            ::....|.:..|  ||..:.....:...:.||...:..||::::.||||.:.:.:||.:
Mouse   770 LQENNRLEILKRKWWEGGKCPKEEDHRAKGLGMENIGGIFVVLICGLIVAIFMAMLEFL 828

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7e	NP_001138176.1	PBPb	218..>313	CDD:214497	27/115 (23%)
Grik4	NP_780690.2	Periplasmic_Binding_Protein_type1	24..402	CDD:385651
		PBP2_iGluR_kainate_KA1	415..785	CDD:270442	69/404 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	931..956

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846219
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740