DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir7e and grid2

DIOPT Version :9

Sequence 1:	NP_001138176.1	Gene:	Ir7e / 7354417	FlyBaseID:	FBgn0259189	Length:	608	Species:	Drosophila melanogaster
Sequence 2:	XP_031759030.1	Gene:	grid2 / 100487676	XenbaseID:	XB-GENE-955038	Length:	1007	Species:	Xenopus tropicalis

Alignment Length:	490	Identity:	97/490 - (19%)
Similarity:	163/490 - (33%)	Gaps:	148/490 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   190 NGSMLVEPDLFPRKL-RNFFGCPLRCALWDVPPFLTLDEDQEEVLRVNGGYEG---RLLLALAEK 250
            |||      |..||| .|..|..||.|.....||:.:.|:   ||.....|:|   .:|.||:..
Frog   426 NGS------LTDRKLENNMRGVVLRVATVLEEPFVMVSEN---VLGKPKKYQGFSIDVLDALSSY 481

  Fly   251 MNF--TIAVRKVHVNMRDEA-------LEMLRRDEVDLTLGGIRQTVARGMVATSSHNY------ 300
            :.|  .|.|...|.....:|       :..|.....|:.:..:..|..|..|...:..|
Frog   482 LGFKYEIYVASDHKYGSPQADGSWNGLIGELLLKRADMGISALTITPDRENVVDFTTRYMDYSVG 546

  Fly   301 ------HQTREVFGVLASSYELSSFDILFYPYRLQIWMGILGVVALSALI----------QLIVG 349
                  .:|.::|..||             |:.|.:|..|.|.|.|..|:          :|.:|
Frog   547 VLLRKAEKTVDMFACLA-------------PFDLSLWACIAGTVLLVGLLVYLLNWLNPPRLQMG 598

  Fly   350 RM---------------------------LRERMGSRFWLNLELVFVGMPLLECPRSHTARLYCV 387
            .|                           |..||....|....|:.:.        |:||.|...
Frog   599 SMTSTTLYNSMWFVYGSFVQQGGEVPYTTLATRMMMGAWWLFALIVIS--------SYTANLAAF 655

  Fly   388 M--------------LMMYTLI-IRTIYQGLLYHLIRTHQLNRWPQTIESLVQKNFTVV-----L 432
            :              |...|.| ..|::...:|..:|...:|  |...:|:..:.:.::     .
Frog   656 LTISRIESSIQSLQDLSRQTDIPYGTVFDSAVYEHVRVKGMN--PFERDSMYSQMWRMINRSNGS 718

  Fly   433 TPIVQEVLDEIPSVQHMRFRLLEANSELDPLYFLEANHQLRQHVTASALDI-FIHFNRLSADKVH 496
            ...|||.|:.|..|:|..:..:...:.|:   ::..|.|          |. |.......||:.:
Frog   719 ENNVQESLEGIQKVKHGNYAFVWDAAVLE---YIAINDQ----------DCSFYTVGNTIADRGY 770

  Fly   497 QRGEQGSGAHFEIVPEDIISMQLT--MYLAKHSFLIDQLNEEIMWMRSVGLLSVWSRWELSESYL 559
            ....|....:.:|..:.|:.:|..  |.:.||.:          |.|:       .:.||..| :
Frog   771 GIALQHGSPYRDIFSQRILELQQNGDMDILKHKW----------WPRN-------GQCELHSS-M 817

  Fly   560 RNEQSFQVLGTMELYAIFLMVLVGLIVGLLVFILE 594
            ..:|....|.......:|.::..|:::...:.::|
Frog   818 DTKQKGSSLDIKSFSGVFCILAAGIVLSCFIAMVE 852

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir7e	NP_001138176.1	PBPb	218..>313	CDD:214497	25/118 (21%)
grid2	XP_031759030.1	Periplasmic_Binding_Protein_type1	28..429	CDD:415822	3/8 (38%)
grid2	XP_031759030.1	PBP2_iGluR_delta_2	440..806	CDD:270449	79/414 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910