Protein Alignment Ir7e and grin2cb

DIOPT Version :9

• Sequence 1: NP_001138176.1
• Gene: Ir7e / 7354417
• FlyBaseID: FBgn0259189
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: XP_009305071.2
• Gene: grin2cb / 100333648
• ZFINID: ZDB-GENE-100308-2
• Length: 1328
• Species: Danio rerio
• Alignment Length: 668
• Identity: 120/668 - (17%)
• Similarity: 209/668 - (31%)
• Gaps: 233/668 - (34%)

  Fly    12 DLSGEQMNHINEFVARAVLHVV-HHYILS-------VTPSLVLTLCCRSNHTCNFYNKMMSTLFR 68
            |.|....::.|..:.|.:|:|. .|..||       ..||:|:....|.||    ::|:.|   .
Zfish   325 DCSSPVKSYANNSLFRHMLNVSWEHKDLSFNSDGYLTNPSMVIIALDRENH----WDKVGS---Y 382

  Fly    69 EWGLAPLQIVNVLRGVPW-------HPVPGRRHFNVIFTDSFAAFEEIRMEYYSREYNYNEHYFI 126
            |.|:  ||    :|...|       .||...||..|      |..|              |..|:
Zfish   383 EGGI--LQ----MRYPVWPRYGSFLEPVSDNRHLTV------ATLE--------------ERPFV 421

  Fly   127 FLQARD-------------RLLQGEMRLIFDYCWRYRLIHCS---IQVQKSNGDILFYSYYPF-- 173
            .:::.|             |........|..:...|..:.|.   |.:.|.....:.:||..:
Zfish   422 IVESVDPATGTCVRNTVPCRRQSNRTESIIGHTEPYTKLCCKGFCIDILKKLSRTIKFSYDLYLV 486

  Fly   174 --GEHGCSDMEPQLINRYNGSMLVEPDLFPRKLRNFFGCPLRCALWDVPPFLTLDEDQEEVLRVN 236
              |:||     ..:...:||.:   .::|.::.....|.            ||::|::.|:
Zfish   487 TNGKHG-----KMVRGVWNGMI---GEVFYKRADMAIGS------------LTINEERSEI---- 527

  Fly   237 GGYEGRLLLALAEKMNFTIAVRKVHVNMRDEALEMLRRDEVDLTLGGIRQTVARGMVATSSHNYH 301
                          ::|::...:..:::                           |||.|:
Zfish   528 --------------VDFSVPFVETGISV---------------------------MVARSN---- 547

  Fly   302 QTREVFGVLASSYELSSFDILFYPYRLQIWMGI----LGVVALSALIQLIVGRMLRER------- 355
                  |.::.|..|.       ||...:|:.:    |.|||::..:......:...|
Zfish   548 ------GTVSPSAFLE-------PYSPAVWVMMFVMCLTVVAVTVFVFEYFSPVGYNRSLVSAKA 599

  Fly   356 -------MGSRFWLNLELVFVGMPLLECPRSHTARLYCVMLMMYTLIIRTIYQGLLYHLIRTHQL 413
                   :|...||...:||.....:|.|:..|:::..::...:.:|....|...|...:...|
Zfish   600 PGGPTFTIGKSVWLLWGIVFNNSVPIENPKGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEQ- 663

  Fly   414 NRWPQTIESLVQKNF-------------TVVLTPIVQEVLDEIPSVQHMRFRLLEANSELDPLYF 465
              :..|:..|..|.|             ||......:.:....|.:.....:..:...|
Zfish   664 --YIDTVSGLSDKKFQKPQEHYPPFRFGTVPNGSTERNIRSNYPDMHTHMIKYNQKGVE------ 720

  Fly   466 LEANHQLRQHVTASALDIFIH----FNRLSA-DKVHQRGEQGSGAHFEIVPEDIISMQLTMYLAK 525
             ||.:.|:    ...||.||:    .|.::. |:..:....|||..|......|
Zfish   721 -EALNSLK----TGKLDAFIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTGYGI----------- 769

  Fly   526 HSFLIDQLNEEIMWMRSVGLL--------------SVWSRWELSESYLRNEQSFQVLGTMELYAI 576
                  .|.::..|.|.:.|.              :||........  :||.....|....:..:
Zfish   770 ------ALQKDSRWKRPIDLALLQFLGDGDTQRLETVWLSGICQNE--KNEVMSSKLDIDNMAGV 826

  Fly   577 FLMVLVGLIVGLLVFILE 594
            |.|:||.:.:.||||..|
Zfish   827 FYMLLVAMGLSLLVFAWE 844

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7e	NP_001138176.1	PBPb	218..>313	CDD:214497	10/94 (11%)
grin2cb	XP_009305071.2	PBP1_iGluR_NMDA_NR2	37..396	CDD:107373	23/83 (28%)
		PBP2_iGluR_NMDA_Nr2	407..808	CDD:270436	83/533 (16%)
		NMDAR2_C	845..>932	CDD:313729	120/668 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591721
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.830