DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir7d and grik1a

DIOPT Version :9

Sequence 1:	NP_001138175.1	Gene:	Ir7d / 7354416	FlyBaseID:	FBgn0259190	Length:	594	Species:	Drosophila melanogaster
Sequence 2:	XP_009303592.1	Gene:	grik1a / 798001	ZFINID:	ZDB-GENE-030131-6502	Length:	919	Species:	Danio rerio

Alignment Length:	267	Identity:	58/267 - (21%)
Similarity:	102/267 - (38%)	Gaps:	80/267 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   190 DIKDG-DLWDVFPRRLKNLHGCPLSVIVWDI--PPYMRINWKSSDP-MDGLDGLDGL---LLRIV 247
            :|||. ::.|....|         ::||..|  .||  :.:|.||. :.|.|..:|.   ||:.:
Zfish   433 EIKDNKNITDSLANR---------TLIVTTILENPY--VMYKKSDKVLYGNDRFEGYCLDLLKEL 486

  Fly   248 ARKMNFT--LKLIPNEPNGLIGGSSFMNGTFTGAYKMLRERRANITIGCAACTPERSTFLEATSP 310
            :..:.||  :||:   .:|..|..: ..|.:.|..:.|.:..|::.:.....|..|...::.:.|
Zfish   487 SNILGFTYEVKLV---TDGKYGAQN-DKGEWNGMVRELIDHIADLAVAPLTITYVREKVIDFSKP 547

  Fly   311 YSQMS--------------------------YIIVLQARGGYSIYEVMLFPFEKYTW-------- 341
            :..:.                          ::.||.|..|.|....::..|..|.|
Zfish   548 FMTLGISILYRKPNGTNPGVFSFLNPLTPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNP 612

  Fly   342 ----------LLLSTILGLHWIV--GSRWRMP----SPILAG-WMLWIFVIRASYEASVFNFI-- 387
                      ||.|...|:..::  ||. .||    :.||.| |..:..:|.:||.|::..|:
Zfish   613 SSEVVENNFTLLNSLWFGVAALMRQGSE-LMPKALSTRILGGIWWFFTLIIISSYTANLAAFLTV 676

  Fly   388 --QNSPV 392
              .:||:
Zfish   677 ERMDSPI 683

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir7d	NP_001138175.1	None
grik1a	XP_009303592.1	Periplasmic_Binding_Protein_Type_1	37..432	CDD:299141
		ANF_receptor	57..398	CDD:279440
		Periplasmic_Binding_Protein_Type_2	446..815	CDD:304360	54/254 (21%)
		Lig_chan	577..846	CDD:278489	27/108 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900