Protein Alignment Ir7d and Ekar

DIOPT Version :10

• Sequence 1: NP_001138175.1
• Gene: Ir7d / 7354416
• FlyBaseID: FBgn0259190
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: NP_001036250.1
• Gene: Ekar / 43806
• FlyBaseID: FBgn0039916
• Length: 899
• Species: Drosophila melanogaster
• Alignment Length: 791
• Identity: 143/791 - (18%)
• Similarity: 246/791 - (31%)
• Gaps: 285/791 - (36%)

  Fly    13 LCK-----VQAVVWPHQHLLEEQLASQISATLQKIFIN--GLAVYNFGVFISTSYEEMDRDRVIL 70
            :||     ||||..|    .:..||:.|::....:.|.  |.:.::|.:.:..|.:        |
  Fly    80 VCKLIRVGVQAVFSP----TDSVLATHINSICDALDIPNIGRSAHDFSINVYPSKQ--------L 132

  Fly    71 VHQVLNRNLYPPNFPVAVVLASKMN------------------RKITAQVFTQLLFVQNAEQAIA 117
            |:...|..:...|:....:|..|.|                  |:::...:...|.....::...
  Fly   133 VNYAFNDVIQYLNWTRFGILHEKENGIINLHQLSRSFHGEVHMRQVSRDSYVSALNEFKGKEIHN 197

  Fly   118 IAEGVNRNGLCVIV--LLTSQPERPIMTKIFTYFMQERYNINVVILVPRLHGVQAFNVRPYTPTS 180
            |....|.||:.:::  :|..|........:||.|..|.|::            :.|.......||
  Fly   198 IIIDTNSNGISILLKNILQQQMNEYKYHYLFTSFDLETYDL------------EDFKYNFVNITS 250

  Fly   181 CSSLEPVEIDI----KDGDLWD--VFPRRLKNLHGCPLSVIV----------------------- 216
            ...::..::.:    ||..|:.  :|.:...||| ...|.|:
  Fly   251 FRLVDTADVGVKQILKDIGLYSHHIFKKPYLNLH-IKKSTILESEPALMFDSVYVFAIGLQTLEQ 314

  Fly   217 ----------------WD----IPPYMR-INWKS-SDPMDGLDG------LDGLLLR---IV--- 247
                            ||    :..|:. :.||. :.|:...||      ||.:.|:   ||
  Fly   315 SHSLTLLNISCEEENSWDGGLSLINYLNAVEWKGLTGPIQFKDGQRVQFKLDLIKLKQHSIVKVG 379

  Fly   248 ------------------ARKMNFTLKLIP-----------------NE---------------- 261
                              |..||.||.:|.                 ||
  Fly   380 EWTPHGHLNITEPSMFFDAGSMNVTLVVITILETPYVMMHYGKNFTGNERFYGFCVDILETISRE 444

  Fly   262 ----------PNGLIGGSSFMNGTFTGAYKMLRERRANITIGCAACTPERSTFLEATSPYSQMS- 315
                      |:...|......|.:.|....|.:.:|::.:|....|..|.:.::.|.|:..:.
  Fly   445 VGFDYILDLVPDRKYGAKDPETGEWNGMVAQLMKYKADLAVGSMTITYARESVIDFTKPFMNLGI 509

  Fly   316 ---------------------------YIIVLQARGGYSIYEV-MLFPFEKYTWLLLS------- 345
                                       |:::........||.| .|.|.|   |..::
  Fly   510 SILFKVPTSEPTRLFSFMNPLAIEIWIYVLIAYFLVSLCIYIVGKLSPIE---WKCINACDLENI 571

  Fly   346 ------TILGLHWIVGSRWRMPSP-----------ILAGWMLWIFVIRASYEAS---------VF 384
                  ::....|.....:...||           |.:.|..:..:|.|||.|:         :.
  Fly   572 SIGNQFSLTDSFWFTIGTFMQQSPDIYPRAMSTRIISSTWGFFSLIIVASYTANLAAFLTTERMI 636

  Fly   385 NFIQN-----SPVKPSPRTLDQALSGG-FRFITDHA--SYR-----MTLKIPSFQGKTLISAGQP 436
            |.|:|     |..:.|..|||   ||. ..|..|..  :|:     |..|.||....|
  Fly   637 NPIENAEDLASQTEISYGTLD---SGSTMTFFRDSVIETYKKIWRSMDNKKPSAFTTT------- 691

  Fly   437 VDVFDALLKAPWKTGAFTSRAFLADHLVRHRKHRNQLVILAEKIVDNMLCMYFPHGSYFAWEINK 501
              ..|.:.:......||...:.:.|::|:...:..|:..|.:   .....:..|.||.:..:|:.
  Fly   692 --YEDGIKRVNQGNYAFLMESTMLDYIVQRDCNLTQIGGLLD---TKGYGIATPKGSPWRDKISL 751

  Fly   502 LLFNMRSFGIFQHHSQILA---WDNLPTTTDTDTPGKRIHSSTESVATGFA-ESMSFVVAALNCL 562
            .:..::..|    ..|:|.   |.|      ||....|.::|.:|.|.... ||:..|...|  :
  Fly   752 AILELQERG----DIQMLYDKWWKN------TDETCTRKNTSKQSKANSLGLESIGGVFVVL--I 804

  Fly   563 MGALCISIVVF 573
            .|.:..::|.|
  Fly   805 AGIIVAAVVAF 815

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7d	NP_001138175.1	None
Ekar	NP_001036250.1	PBP1_iGluR_Kainate	24..390	CDD:380605	59/334 (18%)
		PBP2_iGluR_Kainate	402..771	CDD:270432	67/390 (17%)
		Lig_chan	532..806	CDD:459656	62/303 (20%)