Protein Alignment Ir7d and GluRIIA

DIOPT Version :9

• Sequence 1: NP_001138175.1
• Gene: Ir7d / 7354416
• FlyBaseID: FBgn0259190
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: NP_523484.2
• Gene: GluRIIA / 33788
• FlyBaseID: FBgn0004620
• Length: 907
• Species: Drosophila melanogaster
• Alignment Length: 636
• Identity: 111/636 - (17%)
• Similarity: 213/636 - (33%)
• Gaps: 191/636 - (30%)

  Fly    24 QHLLEEQLASQISATLQKIFINGLAVYNFGV------------------FISTSYEEMDRDRVIL 70
            :.||:..:..::....:..|:..|..:|.|:                  .:..:..|..:.|:..
  Fly   231 KELLKVSIDFKLQGPFRNWFLTHLDTHNSGLRDIYNEDFKANITSVRLKVVDANPFERKKTRLTK 295

  Fly    71 VHQVL-NRNLYPPNFPVAVVLASKMNRKITAQVFTQLLFVQNAEQAIAIAEGV---NRN------ 125
            |.|:| |:.:.|.....|||                 ||..:|...||..:..   ||:
  Fly   296 VDQILGNQTMLPILIYDAVV-----------------LFASSARNVIAAMQPFHPPNRHCGSSSP 343

  Fly   126 ---GLCVIVLLTSQPERPIMTKIFTYFMQ-ERYNINVVILVPRLHGVQAFNVRPYTPTSCSSLEP 186
               |..::..:.:..|..:.....|..|: :.|.       .|:|    ||:..|.||   ..||
  Fly   344 WMLGAFIVNEMKTISEDDVEPHFKTENMKLDEYG-------QRIH----FNLEIYKPT---VNEP 394

  Fly   187 VEIDIKDGDLWDVFPRRLKNLH----GCP---------LSVIVWDIPPYMRI-----NWKSSDPM 233
            :.:...|..:    .:||.||.    |..         .:|:.....||..:     |::..:..
  Fly   395 MMVWTPDNGI----KKRLLNLELESAGTTQDFSEQRKVYTVVTHYEEPYFMMKEDHENFRGREKY 455

  Fly   234 DGLDGLDGLLLRIVARKMNFTLKLIPNEPNGLIGGSSFMNGTFT-------GAYKMLRERRANIT 291
            :|. .:|  |:..::..|.|..:.:      ::.|    ||.:.       |..:.|.:..|.|.
  Fly   456 EGY-AVD--LISKLSELMEFDYEFM------IVNG----NGKYNPETKQWDGIIRKLIDHHAQIG 507

  Fly   292 IGCAACTPERSTFLEATSPYSQMSYIIV-----LQARGGYSIYEVMLFPFEKYTWLLL---STIL 348
            :.....|..|.:.::.|.|:.|:...|:     .:.:..::..|    ||....|:.:   ..|:
  Fly   508 VCDLTITQMRRSVVDFTVPFMQLGISILHYKSPPEPKNQFAFLE----PFAVEVWIYMIFAQLIM 568

  Fly   349 GLHWIVGSR-----WRMPSP----------------------------------------ILAGW 368
            .|.::..:|     |..|:|                                        ||.|
  Fly   569 TLAFVFIARLSYREWLPPNPAIQDPDELENIWNVNNSTWLMVGSIMQQGCDILPRGPHMRILTG- 632

  Fly   369 MLWIFVIR--ASYEASVFNFIQNSPVKPSPRTLDQ----------ALSGG-----FRFITDHASY 416
            |.|.|.:.  ::|.|::..|:.::..:.|.::|..          ::.||     |....|....
  Fly   633 MWWFFALMMLSTYTANLAAFLTSNKWQSSIKSLQDLIEQDKVHFGSMRGGSTSLFFSESNDTDYQ 697

  Fly   417 RMTLKIPSFQGKTLISAGQPVDVFDALLKAPWKTGAFTSRAFLADHL-VRHRKHRN-QLVILAEK 479
            |...::..|......|..:     :.:.:...:.|.:   |||.:.. :.:...|| .|..:.|:
  Fly   698 RAWNQMKDFNPSAFTSTNK-----EGVARVRKEKGGY---AFLMETTSLTYNIERNCDLTQIGEQ 754

  Fly   480 IVDNMLCMYFPHGSYFAWEINKLLFNMRSFGIFQHHSQILAWDNLPTTTDT 530
            |.:....:..|.||.:...::..:..:...|..|.... ..|.|...|.|:
  Fly   755 IGEKHYGLAVPLGSDYRTNLSVSILQLSERGELQKMKN-KWWKNHNVTCDS 804

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7d	NP_001138175.1	None
GluRIIA	NP_523484.2	PBP1_iGluR_Kainate	33..404	CDD:107377	38/203 (19%)
		ANF_receptor	46..386	CDD:279440	32/182 (18%)
		PBP2_iGluR_Kainate	426..796	CDD:270432	64/396 (16%)
		Lig_chan	556..828	CDD:278489	43/259 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462667
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.830