Protein Alignment Ir7d and GluRIIE

DIOPT Version :9

• Sequence 1: NP_001138175.1
• Gene: Ir7d / 7354416
• FlyBaseID: FBgn0259190
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: NP_001036733.1
• Gene: GluRIIE / 318623
• FlyBaseID: FBgn0051201
• Length: 897
• Species: Drosophila melanogaster
• Alignment Length: 690
• Identity: 144/690 - (20%)
• Similarity: 238/690 - (34%)
• Gaps: 222/690 - (32%)

  Fly    23 HQHLLEEQLASQISATLQKIFINGLAVYNFGVFISTSYEEMDRDRVILVHQVLNRNLYPP----- 82
            |...|||...|:.:.|..::|               |.|:|      .|.::|.:..||.
  Fly   252 HSFDLEEYKYSEANITGLRLF---------------SPEKM------AVKELLMKLGYPTDQDEF 295

  Fly    83 ---NFPVAVVLASKMNRKITAQVFTQLL-------FVQNAEQAIAIAEGVN------RNGLCVIV 131
               :.|:.|.:|...:   ..|:|.|.|       ..||..|.   .|.|.      :|.:..:.
  Fly   296 RNGSCPITVEMALTYD---AVQLFAQTLKNLPFKPMPQNCSQR---TESVRDDGSSFKNYMRTLR 354

  Fly   132 LLTSQPERPIMTKIFTYF---MQERYNINVVILVPRLHGVQAFNV----RPYTPTSCSSLEP--V 187
            |.......||      ||   :::.|:::|:.|.|  .|:.....    |.|.|   ..|.|  .
  Fly   355 LTDRLLTGPI------YFEGNVRKGYHLDVIELQP--SGIVKVGTWDEDRQYRP---QRLAPTTA 408

  Fly   188 EIDIKDGDLWDVFPRRLKNLHGCPLSVIVWDIP--PYMRI--NWKSSDPMDGLDGLDGLLLRIVA 248
            :.|..|..|.:            ...:|:..:|  ||.::  .:|..:.....:|....|::.:|
  Fly   409 QFDSVDNSLAN------------KTFIILLSVPNKPYAQLVETYKQLEGNSQYEGYGVDLIKELA 461

  Fly   249 RKMNFTLKLIPNEPNGLIGGSSFMNGTFTGAYK--------MLRE---RRANITIGCAACTPERS 302
            .|:.|....:.       ||:.:      |:|.        ||||   .||::.|.....|.||.
  Fly   462 DKLGFNFTFVN-------GGNDY------GSYNKSTNESTGMLREIMTGRADLAITDLTITSERE 513

  Fly   303 TFLEATSPYSQMSYIIVLQARGGYSIYEVMLF--PF-EKYTWLLLSTILGL---HWIVG----SR 357
            ..|:.|.|:..:. |.:|..:...:..|:..|  || |:..|.|..:.||:   .:|:|    |.
  Fly   514 QALDFTIPFMNLG-IAILYLKPQKATPELFTFMDPFSEEVWWFLGFSFLGVSLSFFILGRLSPSE 577

  Fly   358 WRMPSPIL-----------AGWMLWIFVIRASYEASVFNFIQNSPVKP---SPRTLDQALSGGFR 408
            |..|.|.:           .|..:| |...|..:       |.|.:.|   |.||:  |....|.
  Fly   578 WDNPYPCIEEPEELENQFTLGNSIW-FTTGALLQ-------QGSEIGPKALSTRTV--ASFWWFF 632

  Fly   409 FITDHASYRMTLKIPSF----QGKTLI-SAGQPVDVFDALLKAPWKTGAFTSRAFLADHLVRHRK 468
            .:...:||  |..:.:|    :.::|| |.....|..|.::....|||: |...|:.....|::|
  Fly   633 TLIVVSSY--TANLAAFLTIEKPQSLINSVDDLADNKDGVVYGAKKTGS-TRNFFMTSAEERYKK 694

  Fly   469 HRNQLV-----ILAEKIVDNM-------------------------------------------- 484
             .|:.:     .|.|   |||
  Fly   695 -MNKFMSENPQYLTE---DNMEGVNRVKTNTHYAFLMESTSIEYNTKRECNLKKIGDALDEKGYG 755

  Fly   485 LCMY--FPHGSYFAWEINKLLFNMRSFGIFQHHSQILAWDNLPT---TTDTDTPGKRIHSSTESV 544
            :.|.  :||...|    |..|..::..|:.:.... ..|:.:.|   .|..|.|      ....:
  Fly   756 IAMRKDWPHRGKF----NNALLELQEQGVLEKMKN-KWWNEVGTGICATKEDAP------DATPL 809

  Fly   545 ATGFAESMSFVVAALNCLMGALCISIVVFGLELLSRRRHW 584
            .....|.:.||:...:|.  ||...|:.:.|.::.:..|:
  Fly   810 DMNNLEGVFFVLLVGSCC--ALLYGIISWVLFVMKKAHHY 847

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7d	NP_001138175.1	None
GluRIIE	NP_001036733.1	PBP1_iGluR_Kainate	42..396	CDD:107377	37/178 (21%)
		ANF_receptor	51..382	CDD:279440	34/162 (21%)
		PBP2_iGluR_Kainate	419..790	CDD:270432	85/418 (20%)
		Lig_chan	551..824	CDD:278489	59/300 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462860
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740