Protein Alignment Ir7d and Nmdar2

DIOPT Version :10

• Sequence 1: NP_001138175.1
• Gene: Ir7d / 7354416
• FlyBaseID: FBgn0259190
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: NP_001014714.1
• Gene: Nmdar2 / 31107
• FlyBaseID: FBgn0053513
• Length: 1083
• Species: Drosophila melanogaster
• Alignment Length: 693
• Identity: 123/693 - (17%)
• Similarity: 219/693 - (31%)
• Gaps: 266/693 - (38%)

  Fly    36 SATLQKIFINGLAVYNFGVFISTSY--EEMDRDRVILVHQVLNRNLYPPNFPVAVVLASKMNRKI 98
            ||.|.....|.:.:|::||   .:|  :..:|||
  Fly   367 SAALMNEISNAIKIYSYGV---EAYLTDPANRDR------------------------------- 397

  Fly    99 TAQVFTQLLFVQNAEQAIAIAEGVNR--NGLCVIVLLTSQPERPIMTKIFTYFMQERYNINVV-- 159
              ::.||.|..::        ||..|  ||                 :||..:::   |:::.
  Fly   398 --RLTTQSLSCED--------EGRGRWDNG-----------------EIFFKYLR---NVSIEGD 432

  Fly   160 ILVPRLH----------GVQAFNVRPYTPTS---------CSSLEPVEIDIKDGDLWDVFPRRLK 205
            :..|.:.          .::..|:||.....         ..|.|..::||:| ..|.      .
  Fly   433 LNKPNIEFTADGDLRSAELKIMNLRPSANNKNLVWEEIGVWKSWETQKLDIRD-IAWP------G 490

  Fly   206 NLHGCP--------LSVIVWDIPPYMRINWKSSDPMDGLDGLD-GLLLRIV-------------- 247
            |.|..|        |.:...:..||  ||...:||:.|...:| |:|.|:.
  Fly   491 NSHAPPQGVPEKFHLKITFLEEAPY--INLSPADPVSGKCLMDRGVLCRVAADHEMAADIDVGQA 553

  Fly   248 ---------------------ARKMNFTLKLIPNEPNGLIGGSSFMNGTFTGAYKMLRERRANIT 291
                                 |.::.||.:|:..| :|..|  :..||.:.|....|..|:.::.
  Fly   554 HRNESFYQCCSGFCIDLLEKFAEELGFTYELVRVE-DGKWG--TLENGKWNGLIADLVNRKTDMV 615

  Fly   292 IGCAACTPERSTFLEATSPYSQMSYIIVLQARGGYSIYEVMLFPFEKYTWLLLS---------TI 347
            :.......||...::.:.|:.:....||:..|.|.......|.||:..:|:|:.         .|
  Fly   616 LTSLMINTEREAVVDFSEPFMETGIAIVVAKRTGIISPTAFLEPFDTASWMLVGIVAIQAATFMI 680

  Fly   348 LGLHWIVGSRWRMP-------------SPILAGWMLWIFVIRASYEASVFNFIQNSPVKPSPRTL 399
            ....|:..|.:.|.             |.....|::|..:.:|:....            |||
  Fly   681 FLFEWLSPSGYDMKLYLQNTNVTPYRFSLFRTYWLVWAVLFQAAVHVD------------SPR-- 731

  Fly   400 DQALSGGF--RFIT----------------DHASYRMTLK-------------------IPSFQG 427
                  ||  ||:|                :.|::.:|.:                   .|||:.
  Fly   732 ------GFTSRFMTNVWALFAVVFLAIYTANLAAFMITREEFHEFSGLNDSRLVHPFSHKPSFKF 790

  Fly   428 KTLISAGQPVDVFDALLKAPWKTGAFTSRAF----LADHLVRHRKHRNQLVILAEKIVDNML--- 485
            .|:     |....|:.:...:.......|.:    :||.:...........|....::|.::
  Fly   791 GTI-----PYSHTDSTIHKYFNVMHNYMRQYNKTSVADGVAAVLNGNLDSFIYDGTVLDYLVAQD 850

  Fly   486 --CMYFPHGSYFAWE---------------INKLLFNMRSFGIFQHHSQILAWDNLPTTTDTDTP 533
              |.....||::|..               .||.|...|:.|..:...:.  |     .|.|..|
  Fly   851 EDCRLMTVGSWYAMTGYGLAFSRNSKYVQMFNKRLLEFRANGDLERLRRY--W-----MTGTCRP 908

  Fly   534 GKRIHSSTESVATGFAESMSFVVAALNCLMGALCISIVVFGLE 576
            ||:.|.|::.:|      :...::|...||..:.::.::..||
  Fly   909 GKQEHKSSDPLA------LEQFLSAFLLLMAGILLAALLLLLE 945

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7d	NP_001138175.1	None
Nmdar2	NP_001014714.1	PBP1_iGluR_NMDA_NR2	99..485	CDD:380601	30/181 (17%)
		PBP2_iGluR_NMDA_Nr2	502..908	CDD:270436	77/442 (17%)