Protein Alignment Ir7d and Gria4

DIOPT Version :9

• Sequence 1: NP_001138175.1
• Gene: Ir7d / 7354416
• FlyBaseID: FBgn0259190
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: NP_001106655.1
• Gene: Gria4 / 29629
• RGDID: 61863
• Length: 902
• Species: Rattus norvegicus
• Alignment Length: 762
• Identity: 124/762 - (16%)
• Similarity: 233/762 - (30%)
• Gaps: 254/762 - (33%)

  Fly    28 EEQLASQISATLQKIFINGLAVYNFGVFISTSYEEMDRDRVILVHQVLNRNLYPPNFPVAVVLAS 92
            |.|...|:..:|:...::.|..|.:..|:..    .|.||...:.|.:........:.|:.:...
  Rat   127 ESQFVLQLRPSLRGALLSLLDHYEWNCFVFL----YDTDRGYSILQAIMEKAGQNGWHVSAICVE 187

  Fly    93 KMNRKITAQVFTQL------LFV--------QN-AEQAIAIAE---------------------- 120
            ..|.....|:..:|      .||        || .||.:::.:
  Rat   188 NFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANLGFKDISLERF 252

  Fly   121 ---GVNRNGLCVIVLLTSQPERPIMTKIF------------------TYFMQERYNINVVILVPR 164
               |.|..|..::...|     |::||:.                  .|.....|: .|:::...
  Rat   253 IHGGANVTGFQLVDFNT-----PMVTKLMDRWKKLDQREYPGSETPPKYTSALTYD-GVLVMAET 311

  Fly   165 LHGVQAFNV-------------RPYTPTSCS-----SLEPVEIDIKDGDL------------WDV 199
            ...::...:             .|..|....     :|:.|.|....|::            .||
  Rat   312 FRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNVQFDHYGRRVNYTMDV 376

  Fly   200 F------PRRLKNLHGCPLSVIVWDIP----------------------PYMRINWKSSDPMDGL 236
            |      ||::...:.....|::.|:|                      ||:... |:.:..:|.
  Rat   377 FELKSTGPRKVGYWNDMDKLVLIQDMPTLGNDTAAIENRTVVVTTIMESPYVMYK-KNHEMFEGN 440

  Fly   237 DGLDGLLLRI---VARKMNFTLKLIPNEPNGLIGGSSFMNGTFTGAYKMLRERRANITIGCAACT 298
            |..:|..:.:   :|:.:....| |...|:|..|........:.|....|...:|.|.|.....|
  Rat   441 DKYEGYCVDLASEIAKHIGIKYK-IAIVPDGKYGARDADTKIWNGMVGELVYGKAEIAIAPLTIT 504

  Fly   299 PERSTFLEATSPYSQMSYIIVL----QARGG---------YSIYEVMLFPF--EKYTWLLLSTIL 348
            ..|...::.:.|:..:...|::    :::.|         |.|:..::|.:  ......|:|...
  Rat   505 LVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFS 569

  Fly   349 GLHW---------------------IVGSRW---------------RMPSPILAGWMLWIF--VI 375
            ...|                     |..|.|               |..|..:.|.:.|.|  :|
  Rat   570 PYEWHTEEPEDGKEGPSDQPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLII 634

  Fly   376 RASYEASVFNFI----QNSPVKPSP----------RTLDQALSGGFRFITDHASYRMTLKIPSFQ 426
            .:||.|::..|:    ..||::.:.          .|||...:..|        :|.: ||..::
  Rat   635 ISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEF--------FRRS-KIAVYE 690

  Fly   427 GK-TLISAGQPVDVFDALLKAPWKTGAFTSRAFLADHLVRHRKHRNQLVILAEKIVDNML----- 485
            .. |.:.:.:|              ..||...  |:.:.|.||.:.:...|.|..::..:
  Rat   691 KMWTYMRSAEP--------------SVFTRTT--AEGVARVRKSKGKFAFLLESTMNEYIEQRKP 739

  Fly   486 C---------------MYFPHGSYFAWEINKLLFNMRSFGIFQHHSQILAWDNLPTTTDTDTPGK 535
            |               :..|.||.....:|..:..:...|:.........:|.          |:
  Rat   740 CDTMKVGGNLDSKGYGVATPKGSSLRNAVNLAVLKLNEQGLLDKLKNKWWYDK----------GE 794

  Fly   536 RIHSSTESVATGFAESMSFVVAALNCLMGALCISIVVFGLELLSRRR 582
            ......:|.....|.|:|.|......|:|.|.::::|..:|...:.|
  Rat   795 CGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSR 841

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7d	NP_001138175.1	None
Gria4	NP_001106655.1	PBP1_iGluR_AMPA_GluR4	28..398	CDD:107383	42/280 (15%)
		ANF_receptor	39..380	CDD:279440	40/262 (15%)
		PBP2_iGluR_AMPA_GluR4	414..795	CDD:270445	68/417 (16%)
		Lig_chan	546..825	CDD:278489	52/313 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900