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Protein Alignment Ir7d and GRIA4

DIOPT Version :9

Sequence 1:	NP_001138175.1	Gene:	Ir7d / 7354416	FlyBaseID:	FBgn0259190	Length:	594	Species:	Drosophila melanogaster
Sequence 2:	NP_000820.4	Gene:	GRIA4 / 2893	HGNCID:	4574	Length:	902	Species:	Homo sapiens

Alignment Length:	506	Identity:	89/506 - (17%)
Similarity:	164/506 - (32%)	Gaps:	160/506 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   198 DVF------PRRLKNLHGCPLSVIVWDIP----------------------PYMRINWKSSDPMD 234
            |||      ||::...:.....|::.|:|                      ||:... |:.:..:
Human   375 DVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVTTIMESPYVMYK-KNHEMFE 438

  Fly   235 GLDGLDGLLLRI---VARKMNFTLKLIPNEPNGLIGGSSFMNGTFTGAYKMLRERRANITIGCAA 296
            |.|..:|..:.:   :|:.:....| |...|:|..|........:.|....|...:|.|.|....
Human   439 GNDKYEGYCVDLASEIAKHIGIKYK-IAIVPDGKYGARDADTKIWNGMVGELVYGKAEIAIAPLT 502

  Fly   297 CTPERSTFLEATSPYSQMSYIIVL----QARGG---------YSIYEVMLFPF--EKYTWLLLST 346
            .|..|...::.:.|:..:...|::    :::.|         |.|:..::|.:  ......|:|.
Human   503 ITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSR 567

  Fly   347 ILGLHW---------------------IVGSRW---------------RMPSPILAGWMLWIF-- 373
            .....|                     |..|.|               |..|..:.|.:.|.|
Human   568 FSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTL 632

  Fly   374 VIRASYEASVFNFI----QNSPVKPSP----------RTLDQALSGGFRFITDHASYRMTLKIPS 424
            :|.:||.|::..|:    ..||::.:.          .|||...:..|        :|.: ||..
Human   633 IIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEF--------FRRS-KIAV 688

  Fly   425 FQGK-TLISAGQPVDVFDALLKAPWKTGAFTSRAFLADHLVRHRKHRNQLVILAEKIVDNML--- 485
            ::.. |.:.:.:|              ..||...  |:.:.|.||.:.:...|.|..::..:
Human   689 YEKMWTYMRSAEP--------------SVFTRTT--AEGVARVRKSKGKFAFLLESTMNEYIEQR 737

  Fly   486 --C---------------MYFPHGSYFAWEINKLLFNMRSFGIFQHHSQILAWDNLPTT--TDTD 531
              |               :..|.||.....:|..:..:...|:.         |.|...  .|..
Human   738 KPCDTMKVGGNLDSKGYGVATPKGSSLRTPVNLAVLKLSEAGVL---------DKLKNKWWYDKG 793

  Fly   532 TPGKRIHSSTESVATGFAESMSFVVAALNCLMGALCISIVVFGLELLSRRR 582
            ..|.:...|.:..:   |.|:|.|......|:|.|.::::|..:|...:.|
Human   794 ECGPKDSGSKDKTS---ALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSR 841

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.