Protein Alignment Ir7d and glr-1

DIOPT Version :9

• Sequence 1: NP_001138175.1
• Gene: Ir7d / 7354416
• FlyBaseID: FBgn0259190
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: NP_498887.2
• Gene: glr-1 / 176204
• WormBaseID: WBGene00001612
• Length: 962
• Species: Caenorhabditis elegans
• Alignment Length: 595
• Identity: 109/595 - (18%)
• Similarity: 191/595 - (32%)
• Gaps: 214/595 - (35%)

  Fly    83 NFPVAVV-LASKMNRKITAQVFTQLLFVQNAEQAIAIAEGV----NRNGLCVIVLLTSQPERPIM 142
            ||.|::| |.|  |.|.|.          |:::.:|..:||    ||.        .:|..|.
 Worm   408 NFDVSIVDLVS--NTKATF----------NSKEVLAWRQGVGFFSNRT--------VAQHSRK-- 450

  Fly   143 TKIFTYFMQERYNINVVILVPRLHGVQAFNVRPYTPTSCSSLEPVEIDIKDGDLWDVFPRRLKNL 207
                   .|..:..|.||::..|       |.|:.......||                  :.||
 Worm   451 -------SQNDHKDNQVIVLTNL-------VAPFVMIKRECLE------------------MANL 483

  Fly   208 HGCPLSVIVWDIPPYMRINWKSSDPMDGLDGLDGL---LLRIVARKM---NFTLKLIPNEPNGLI 266
            ..|                       .|.:..:|.   ||:::|.|:   |:.:||      |..
 Worm   484 TEC-----------------------QGNNKFEGFCIDLLKLLADKIEEFNYEIKL------GTK 519

  Fly   267 GGSSFMNGTFTGAYKMLRERRANITIGCAACTPERSTFLEATSPY-------------------- 311
            .||...:|::.|....|...||:..:.......||...::.:.|:
 Worm   520 AGSKQADGSWDGMIGELLSGRAHAVVASLTINQERERVVDFSKPFMTTGISIMIKKPDKQEFSVF 584

  Fly   312 ------SQMSYIIVLQARGGYSIYEVMLFPFEKYTWLLLSTILG-------------LHWIVGSR 357
                  |...::.::.|..|.|:...::..|..|.|.:..|..|             |.:.:.:.
 Worm   585 SFMQPLSTEIWMYIIFAYIGVSVVIFLVSRFSPYEWRVEETSRGGFTISNDFSVYNCLWFTLAAF 649

  Fly   358 WRMPSPIL----------AGWMLWIFVIRASYEASVFNFI----QNSPVKPSPRTLDQA-----L 403
            .:..:.||          :.|..:..:|.:||.|::..|:    ..:|::.......|:     :
 Worm   650 MQQGTDILPRSISGRIASSAWWFFTMIIVSSYTANLAAFLTLEKMQAPIESVEDLAKQSKIKYGI 714

  Fly   404 SGG------FRFITDHASYRMTLKIPSFQGKTLISAGQPVDVFDALLKAPWKTGAFTSRAFLADH 462
            .||      |::.:.....||        .:.:.|...||.|                 |..|:.
 Worm   715 QGGGSTASFFKYSSVQIYQRM--------WRYMESQVPPVFV-----------------ASYAEG 754

  Fly   463 LVRHRKHRNQLVILAE----------------KIVDNMLCMYF----PHGSYFAWEINKLLFNMR 507
            :.|.|.|:.:...|.|                |:..|:..:.:    |.||.:...||..:..::
 Worm   755 IERVRSHKGRYAFLLEATANEYENTRKPCDTMKVGANLNSIGYGIATPFGSDWKDHINLAILALQ 819

  Fly   508 SFGIFQHHSQILAWDNLPTTTDTDTPGKRIHSSTESVATGFAESMSFVVAALNCLMGALCISIVV 572
            ..|..:.......:|.    ...|. |..:..|:.|:      ::|.|......|||.:.||::.
 Worm   820 ERGELKKLENKWWYDR----GQCDA-GITVDGSSASL------NLSKVAGIFYILMGGMVISMLA 873

  Fly   573 FGLELLSRRR 582
            ...|.|.|.|
 Worm   874 ALGEFLYRSR 883

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7d	NP_001138175.1	None
glr-1	NP_498887.2	PBP1_iGluR_AMPA	10..439	CDD:107375	13/42 (31%)
		ANF_receptor	44..417	CDD:279440	4/8 (50%)
		Periplasmic_Binding_Protein_Type_2	457..832	CDD:304360	75/453 (17%)
		Lig_chan	593..867	CDD:278489	53/309 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900