Protein Alignment Ir7d and Grin2b

DIOPT Version :9

• Sequence 1: NP_001138175.1
• Gene: Ir7d / 7354416
• FlyBaseID: FBgn0259190
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: NP_001350679.1
• Gene: Grin2b / 14812
• MGIID: 95821
• Length: 1482
• Species: Mus musculus
• Alignment Length: 490
• Identity: 89/490 - (18%)
• Similarity: 159/490 - (32%)
• Gaps: 176/490 - (35%)

  Fly    38 TLQKIFINGLAVYNFGVFISTSYEEMD-------RDRVILV----HQVLNRNLYPPNFPVA---- 87
            |:...|..||        ||.||:|.|       ||.:.::    ..:|:.:.:.|. |.:
Mouse   268 TVPSEFPTGL--------ISVSYDEWDYGLPARVRDGIAIITTAASDMLSEHSFIPE-PKSSCYN 323

  Fly    88 -----VVLASKMNRKITAQVF--TQLLFVQNAEQAIAIAEGVNRNGLCVIVLLTSQPERPIMTKI 145
                 :..::.:||.:....|  ..|.|.:         :|...:...||:||..:.:...:.|.
Mouse   324 THEKRIYQSNMLNRYLINVTFEGRNLSFSE---------DGYQMHPKLVIILLNKERKWERVGKW 379

  Fly   146 FTYFMQERYNINVVILVPRLHGVQAFNVRPYTPTSCSSLEPVEIDIKDGDLWDVFPRRLKNLHGC 210
            ....:|.:|.:                    .|..|...|..|.|                 |
Mouse   380 KDKSLQMKYYV--------------------WPRMCPETEEQEDD-----------------H-- 405

  Fly   211 PLSVIVWDIPPYMRINWKSSDPMDG------------------LDGLDGL-----------LLRI 246
             ||::..:..|::.:  :|.||:.|                  .|...|.           :|:.
Mouse   406 -LSIVTLEEAPFVIV--ESVDPLSGTCMRNTVPCQKRIISENKTDEEPGYIKKCCKGFCIDILKK 467

  Fly   247 VARKMNFT--LKLIPNEPNGLIGGSSFMNGTFTGAYKMLRERRANITIGCAACTPERSTFLEATS 309
            :::.:.||  |.|:.|..:|     ..:|||:.|....:..:||.:.:|......|||..::.:.
Mouse   468 ISKSVKFTYDLYLVTNGKHG-----KKINGTWNGMIGEVVMKRAYMAVGSLTINEERSEVVDFSV 527

  Fly   310 PYSQMSYIIVLQARGGYSIYEVMLFPFEKYTWLLLSTILGLHWIVGSRWRMPSPILAGWMLWIFV 374
            |:.:....:::....|.......|.||....|:::..:|                        .:
Mouse   528 PFIETGISVMVSRSNGTVSPSAFLEPFSADVWVMMFVML------------------------LI 568

  Fly   375 IRASYEASVFNFIQNSPVKPSPRTLDQALSGGFRFITDHASYRMTLKIPSFQ-GKTL-------- 430
            :.|   .:||.|...|||..:....|....||                |||. ||.:
Mouse   569 VSA---VAVFVFEYFSPVGYNRCLADGREPGG----------------PSFTIGKAIWLLWGLVF 614

  Fly   431 ---ISAGQPVDVFDALLKAPWKTGAFTSRAFLADH 462
               :....|......::.:.|   ||.:..|||.:
Mouse   615 NNSVPVQNPKGTTSKIMVSVW---AFFAVIFLASY 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7d	NP_001138175.1	None
Grin2b	NP_001350679.1	PBP1_iGluR_NMDA_NR2	33..388	CDD:380601	27/137 (20%)
		PBP2_iGluR_NMDA_Nr2	403..803	CDD:270436	57/317 (18%)
		NMDAR2_C	840..1482	CDD:402274

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910