Protein Alignment Ir7d and Grik5

DIOPT Version :9

• Sequence 1: NP_001138175.1
• Gene: Ir7d / 7354416
• FlyBaseID: FBgn0259190
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: XP_030098003.1
• Gene: Grik5 / 14809
• MGIID: 95818
• Length: 1003
• Species: Mus musculus
• Alignment Length: 697
• Identity: 133/697 - (19%)
• Similarity: 233/697 - (33%)
• Gaps: 219/697 - (31%)

  Fly    61 EEMDRDRVILV---------HQVLNRNL-------YPPNFPV---AVVLASKMNRKITAQVFTQL 106
            :|:..|:|..:         |.||..:|       :|.:.|:   .|:.||::.  :|:..:..:
Mouse   204 KEIRDDKVSTIIIDANASISHLVLRLSLNLSSPLGFPRSLPLGLSCVLQASELG--MTSAFYKYI 266

  Fly   107 LFVQNAEQAIAIAEGV---NRNGLCVIVLLTSQPERPIMTKIFTYFMQERYNIN----------- 157
            |  ...:..|...:|:   :.|.|...:..||.|..|...:......:|....:
Mouse   267 L--TTMDFPILHLDGIVEDSSNILGFSMFNTSHPFYPEFVRSLNMSWRENCEASTYPGPALSAAL 329

  Fly   158 -------VVILVPRLHGVQAFNVRPYTPTSC----------SSLEPVEIDIKDG----------- 194
                   ||..|..|:..|...|:|...||.          :.|..||.|...|
Mouse   330 MFDAVHVVVSAVRELNRSQEIGVKPLACTSANIWPHGTSLMNYLRMVEYDGLTGRVEFNSKGQRT 394

  Fly   195 -----------------DLWDVFPRRLKNLHGCPLSV-----------IVWDI--PPYM--RINW 227
                             .:|  :..|...::...|.:           :|..|  .||:  |.|:
Mouse   395 NYTLRILEKSRQGHREIGVW--YSNRTLAMNATTLDINLSQTLANKTLVVTTILENPYVMRRPNF 457

  Fly   228 KSSDPMDGLDGLDGLLLRIVARKMNFTLKLIPNEPNGLIGGSSFMNGTFTGAY-KMLRERRANIT 291
            ::....:..:|....:||.:|..:.|..:|...| :||.|... .||::||.. :::..::|::.
Mouse   458 QALSGNERFEGFCVDMLRELAELLRFRYRLRLVE-DGLYGAPE-PNGSWTGMVGELINRQKADLA 520

  Fly   292 IGCAACTPERSTFLEATSPYSQMS----YIIVLQARGGYSIYEVMLFPFEKYTWLLL-------S 345
            :.....|.||...::.:.|:..:.    |.:.:..:.||..:   |.||....||.:       |
Mouse   521 VAAFTITAEREKVIDFSKPFMTLGISILYRVHMGRKPGYFSF---LDPFSPAVWLFMLLAYLAVS 582

  Fly   346 TILGLHWIVGSR-----WRMPSPILAG-------------------------------------- 367
            .:|    .:.:|     |..|.|.|..
Mouse   583 CVL----FLAARLSPYEWYNPHPCLRARPHILENQYTLGNSLWFPVGGFMQQGSEIMPRALSTRC 643

  Fly   368 ----WMLWIFVIRASYEASVFNFI----QNSPVKPSPRTLDQALSGGFRFITDHASYRMTLKIPS 424
                |..:..:|.:||.|::..|:    ...||:.:....||.   ...:.|.||...||.
Mouse   644 VSGVWWAFTLIIISSYTANLAAFLTVQRMEVPVESADDLADQT---NIEYGTIHAGSTMTF---- 701

  Fly   425 FQGK---------TLISAGQPVDVFDALLKAPWK--TGAFTSR-AFLADHLVR--HRKHRNQLVI 475
            ||..         ..:.:.|| .||   :|:..:  .....|| |||.:..:.  ||:....|..
Mouse   702 FQNSRYQTYQRMWNYMQSKQP-SVF---VKSTEEGIARVLNSRYAFLLESTMNEYHRRLNCNLTQ 762

  Fly   476 LAEKIVDNMLCMYFPHGSYFAWEINKLLFNMRSFGIFQHHSQILA---WDNLPTTTDTDTPGKRI 537
            :...:......:..|.||.|..||...:..::.    .:..:||.   |:           |.|.
Mouse   763 IGGLLDTKGYGIGMPLGSPFRDEITLAILQLQE----NNRLEILKRKWWE-----------GGRC 812

  Fly   538 HSSTESVATGFA-ESMSFVVAALNCLMGALCISIVVFGLELL-SRRR 582
            ....:..|.|.. |::..:...|.|   .|.|::.|..:|.: |.||
Mouse   813 PKEEDHRAKGLGMENIGGIFVVLIC---GLIIAVFVAVMEFIWSTRR 856

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7d	NP_001138175.1	None
Grik5	XP_030098003.1	PBP1_iGluR_Kainate_KA1_2	23..424	CDD:380616	39/225 (17%)
		Periplasmic_Binding_Protein_Type_2	437..808	CDD:419667	78/394 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810