DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ir7d and Grik3

DIOPT Version :9

Sequence 1:NP_001138175.1 Gene:Ir7d / 7354416 FlyBaseID:FBgn0259190 Length:594 Species:Drosophila melanogaster
Sequence 2:NP_001074566.1 Gene:Grik3 / 14807 MGIID:95816 Length:919 Species:Mus musculus


Alignment Length:298 Identity:62/298 - (20%)
Similarity:112/298 - (37%) Gaps:77/298 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   213 SVIVWDI--PPYMRINWKSSDPMDGLDGLDGL---LLRIVARKMNFT--LKLIPNEPNGLIGGSS 270
            |:||..:  .|::... ||...:.|.|..:|.   ||:.:|..:.|:  ::|:   .:|..|...
Mouse   435 SLIVTTVLEEPFVMFR-KSDRTLYGNDRFEGYCIDLLKELAHILGFSYEIRLV---EDGKYGAQD 495

  Fly   271 FMNGTFTGAYKMLRERRANITIGCAACTPERSTFLEATSPYSQMS-------------------- 315
             ..|.:.|..|.|.:.:|::.:.....|..|...::.:.|:..:.                    
Mouse   496 -DKGQWNGMVKELIDHKADLAVAPLTITHVREKAIDFSKPFMTLGVSILYRKPNGTNPSVFSFLN 559

  Fly   316 ------YIIVLQARGGYSIYEVMLFPFEKYTWLLLS-------------TILGLHWI-VGSRWR- 359
                  ::.||.|..|.|....::..|..|.|....             |:|...|. :||..: 
Mouse   560 PLSPDIWMYVLLAYLGVSCVLFVIARFSPYEWYDAHPCNPGSEVVENNFTLLNSFWFGMGSLMQQ 624

  Fly   360 ----MPSPI---LAGWMLWIF--VIRASYEASVFNFI----QNSPVKPSPRTLDQALSGGFRFIT 411
                ||..:   :.|.:.|.|  :|.:||.|::..|:    ..||: .|...|.:.....:..:.
Mouse   625 GSELMPKALSTRIIGGIWWFFTLIIISSYTANLAAFLTVERMESPI-DSADDLAKQTKIEYGAVK 688

  Fly   412 DHASYRMTL----KIPSFQGKTLISAGQPVDVFDALLK 445
            |.|:  ||.    ||.:|:......:.:|    .||:|
Mouse   689 DGAT--MTFFKKSKISTFEKMWAFMSSKP----SALVK 720

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ir7dNP_001138175.1 None
Grik3NP_001074566.1 PBP1_iGluR_Kainate_GluR5_7 34..417 CDD:107388
PBP2_iGluR_Kainate_GluR7 433..801 CDD:270441 62/298 (21%)
Glutamate binding. /evidence=ECO:0000250 690..692 0/1 (0%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1052
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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