DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir94d and grin3ba

DIOPT Version :9

Sequence 1:	NP_001138099.1	Gene:	Ir94d / 7354412	FlyBaseID:	FBgn0259193	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	XP_021323058.1	Gene:	grin3ba / 566411	ZFINID:	ZDB-GENE-070912-354	Length:	1118	Species:	Danio rerio

Alignment Length:	550	Identity:	98/550 - (17%)
Similarity:	169/550 - (30%)	Gaps:	234/550 - (42%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 WQ--LPVS-----VLQIKEH----SRETYSLLENPSHNVLTIAFVNDSPEDILEILYRNLRMLNT 106
            ||  |||:     |:.:.||    :||.....:.|:..:......|:|  ::|..|:|.|...|:
Zfish   447 WQAGLPVAGSRLRVVTLVEHPFVFTREVDEEGQCPAGQLCLDPQTNNS--EVLNQLFRELEQTNS 509

  Fly   107 QPVLLVIRKSTIRVNSLLEWCWHHQLLKVVAIAQDFMESLIVYSYNPFPVLQFIERRLDNSTVIF 171
            ..:...:||           |                    .|.|           .:|    :.
Zfish   510 SSLPTDMRK-----------C--------------------CYGY-----------CID----LL 528

  Fly   172 EKRLENLHGYEVPIALGGSSPRLIVYRDLEGKL------IFSGPVGNFMKSFEQRYNCRLVQPYP 230
            ||..|::| :|..:.:.|           :||.      .:||.||:.:..         |....
Zfish   529 EKLAEDMH-FEFDLYIVG-----------DGKYGAWKGGRWSGLVGDLLSG---------VADMA 572

  Fly   231 FDESAISPARDLIASVQNGSVQIALGAIY----PQVPYTGYSYPIELMSW----------CLMMP 281
            ....:|:.||..:....:.....:||.:.    ...|...:.:|:....|          .|.:.
Zfish   573 VTSFSINSARSRVIDFTSPFFSTSLGILVRSKDTAAPIGAFMWPLHWSMWVGIFVALHITALFIT 637

  Fly   282 VPE------EVPHSQLYSMVFS---------PMAFGITIVA--------------------MVLI 311
            :.|      ..||.:....|||         .:.||.|:.:                    :||.
Zfish   638 LYEWNSPFGMTPHGRNRIRVFSYSSALNLCYAILFGRTVASKTPKCWTGRFLMNLWAIFCLLVLS 702

  Fly   312 SLTLSMA-----------------LRLHGYRVSFSEYFLHDSCLRGVLSQSF---YEVLRAPALI 356
            |.|.::|                 ::||...:.|....:.:|.....:.:||   :|.:|.
Zfish   703 SYTANLAAVMVGEKTFEEVSGIHDVKLHHPSLGFRFGTVRESSAEDYVKKSFPEMHEYMRR---- 763

  Fly   357 KAMYLVICLLGLLITSWYN-----SYFSTFVTSAPRF------PQLTSYESIRHSNIKIV----- 405
                             :|     ...||..|..|:.      ..|..||....::.|::
Zfish   764 -----------------FNKPTTPDGVSTLKTDPPQLDAFIMDKALLDYEVSIDADCKLLTVGKP 811

  Fly   406 -------IWKPEYEMLLFFSENMEKYSSIFQLQEDYKEFLHLRDSFDTRYGYMMPMEKW-SLMKE 462
                   |..|:...|   :.|:.:|.|.:: .:.|.:.||               :|| .::..
Zfish   812 FAIEGYGIGLPQNSPL---TRNVSEYVSRYK-SDGYMDMLH---------------DKWYKVVPC 857

  Fly   463 QQRVFS------------SPLFSLQDDLCV 480
            .:|||:            |.||.|   |||
Zfish   858 GKRVFAVTETLQMGIQHFSGLFVL---LCV 884

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir94d	NP_001138099.1	None
grin3ba	XP_021323058.1	Periplasmic_Binding_Protein_Type_1	26..428	CDD:324556
grin3ba	XP_021323058.1	PBP2_iGluR_NMDA_Nr3	457..852	CDD:270438	82/503 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591822
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840