DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir94d and grik1b

DIOPT Version :9

Sequence 1:	NP_001138099.1	Gene:	Ir94d / 7354412	FlyBaseID:	FBgn0259193	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	XP_690040.5	Gene:	grik1b / 561540	ZFINID:	ZDB-GENE-070821-1	Length:	906	Species:	Danio rerio

Alignment Length:	206	Identity:	47/206 - (22%)
Similarity:	83/206 - (40%)	Gaps:	50/206 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   369 LITSWYNSYFSTFVTSAPRFPQLTSY----ESIRHSNIKIV------IWKPEYEMLLFFSENMEK 423
            ::|.:|:.:|:|          |..|    |..|:|.:.:.      |..|:...:      :||
Zfish   275 MMTEYYHFFFTT----------LDLYSLDLEPFRYSGVNMTGFRLLNIDNPQVASV------VEK 323

  Fly   424 YSSIFQLQEDYKEFLHLRDSFDTRYGYMMPMEKWSLMKEQQRVFSSPLFSLQDDLCVFHTVPIVF 488
            : |:.:||...|....|:|...|....:|....:.:....||.....:.|||   |..|. |..|
Zfish   324 W-SMERLQAPPKPETGLQDGMMTTEAALMYDAVYMVAAASQRASQITVSSLQ---CHRHK-PWRF 383

  Fly   489 PMVKNSIFKEP-----FDRLILDVTATGLLSRWRDMSFTEMIKAGQLGLEDRGHPKEFRAMKVGD 548
            .....|:|||.     ..::|::.| .||.   :|... ::|...:.|||        :.::.|.
Zfish   384 GSRFISMFKEAQWNGLTGQIIINKT-DGLR---KDFDL-DIISLKEDGLE--------KPLESGR 435

  Fly   549 LIQIWRFVG-W 558
            ..::|:.:| |
Zfish   436 FNKVWKKIGVW 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir94d	NP_001138099.1	None
grik1b	XP_690040.5	Periplasmic_Binding_Protein_Type_1	62..455	CDD:299141	47/206 (23%)
		ANF_receptor	80..423	CDD:279440	40/173 (23%)
		Periplasmic_Binding_Protein_Type_2	471..840	CDD:304360
		Lig_chan	602..871	CDD:278489
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591606
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930