Protein Alignment Ir94d and grin2bb

DIOPT Version :9

• Sequence 1: NP_001138099.1
• Gene: Ir94d / 7354412
• FlyBaseID: FBgn0259193
• Length: 593
• Species: Drosophila melanogaster
• Sequence 2: NP_001121809.1
• Gene: grin2bb / 559976
• ZFINID: ZDB-GENE-061207-27
• Length: 1770
• Species: Danio rerio
• Alignment Length: 670
• Identity: 122/670 - (18%)
• Similarity: 229/670 - (34%)
• Gaps: 248/670 - (37%)

  Fly     3 QLHLLLVALVLLSPGGDSFYHSLIHHLNRELKIEYVLLLGNFDTTWLDILWQLPVSVLQIKEH-- 65
            |:|..||.::                ||:|.:.|.|   |.::.           ..|.:|.|
Zfish   434 QMHPKLVIIL----------------LNKERQYERV---GKWEN-----------GSLAMKYHVW 468

  Fly    66 -SRETYSLLENPSHNVLTIAFVNDSPEDILEIL--YRNLRMLNTQPVLLVIRKSTIRVNS--LLE 125
             ..|.||..|....:.|:|..:.::|..|:|.:  .....|.||.|....::...:..:|  .::
Zfish   469 PRFELYSDAEEREDDHLSIVTLEEAPFVIVEDVDPLSGTCMRNTVPCRKQLKLQNLTGDSGIYIK 533

  Fly   126 WC---WHHQLLKVVAIAQDFMESLIVYSYNPFPVLQFIERRLDNST---VIFEKRLENLHGYEVP 184
            .|   :...:||.:|       ..:.::|:.:.|......:..|.|   ::.|..|:|.|
Zfish   534 RCCKGFCIDILKKIA-------KSVKFTYDLYLVTNGKHGKKINGTWNGMVGEVVLKNAH----- 586

  Fly   185 IALGGSSPRLIVYRDLEGKLIFSGPVGNFMKSFEQRYNCRLVQPYPFDESAISPARDLIASVQNG 249
            :|:|.    |.:..:....:.||                     .||.|:.||    ::.|..||
Zfish   587 MAVGS----LTINEERSEVIDFS---------------------VPFIETGIS----VMVSRSNG 622

  Fly   250 SVQIALGAIYPQVPYTGYSYPIELMSWCLMMPVPEEVPHSQLYSMVFSPMAFGITIVAMVLISLT 314
            :|.                                  |     |....|.:..:.::..|::.:.
Zfish   623 TVS----------------------------------P-----SAFLEPFSADVWVMMFVMLLIV 648

  Fly   315 LSMALRLHGYRVSFSEYFL---HDSCL---RGVLSQSFYEVLRAPALIKAMYLVICLLGLLITSW 373
            .::|       |...|||.   ::.||   |.....||       .:.||::|   |.||:
Zfish   649 SAVA-------VFVFEYFSPVGYNRCLADGREPGGPSF-------TIGKAIWL---LWGLV---- 692

  Fly   374 YNSYFSTFVTSAP-RFPQLTSYESIRHSNIKIVIWKPEYEMLLF---FSENMEKYSSIFQLQEDY 434
                   |..|.| :.|:.|:      |.|.:.:|  .:..::|   ::.|:    :.|.:||:|
Zfish   693 -------FNNSVPVQNPKGTT------SKIMVSVW--AFFAVIFLASYTANL----AAFMIQEEY 738

  Fly   435 ---------KEFLH---------------------LRDSFDTRYGYMMPMEKWSLMKEQQRVFSS 469
                     |:|.|                     :|:::...:.||....:.::.:....:.|.
Zfish   739 VDQVTGLSDKKFQHPNDFSPPFRFGTVPNGSTERNIRNNYKEMHSYMTSFHQKNVNEALHSLKSG 803

  Fly   470 PLFSL------------QDDLC---------VFHTVPIVFPMVKNSIFKEPFDRLILDVTATGLL 513
            .|.:.            :|:.|         :|.|......:.|:|.:|...|..||.:...|
Zfish   804 KLDAFIYDAAVLNYMAGRDEGCKLVTIGSGYIFATTGYGIAIQKDSGWKRAVDLAILQLFGDG-- 866

  Fly   514 SRWRDMSFTEMIKAGQLGLEDRGHPKEFRAMK----VGDLIQIWRFVGWMLGLATIVFLLELICF 574
                     ||.:...|.|....|.::...|.    |.::..::..:|..:.|:.|.|:.|.:.:
Zfish   867 ---------EMEELEALWLTGICHNEKNEVMSSQLDVDNMAGVFYMLGAAMALSLITFIAEHLFY 922

  Fly   575 WRHKMWQNMKYMF---CRNK 591
            |:      :::.|   |..|
Zfish   923 WQ------LRFCFMGVCSGK 936

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir94d	NP_001138099.1	None
grin2bb	NP_001121809.1	PBP1_iGluR_NMDA_NR2	107..470	CDD:107373	13/65 (20%)
		ANF_receptor	138..442	CDD:279440	4/7 (57%)
		PBP2_iGluR_NMDA_Nr2	482..882	CDD:270436	93/530 (18%)
		Lig_chan	636..908	CDD:278489	58/322 (18%)
		NMDAR2_C	919..1770	CDD:287527	4/24 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591428
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840