Protein Alignment Ir94d and Grik

DIOPT Version :9

• Sequence 1: NP_001138099.1
• Gene: Ir94d / 7354412
• FlyBaseID: FBgn0259193
• Length: 593
• Species: Drosophila melanogaster
• Sequence 2: NP_001262788.1
• Gene: Grik / 42476
• FlyBaseID: FBgn0038840
• Length: 907
• Species: Drosophila melanogaster
• Alignment Length: 636
• Identity: 118/636 - (18%)
• Similarity: 228/636 - (35%)
• Gaps: 144/636 - (22%)

  Fly    36 EYVLLLGNFDTTWLDI------------LWQLPVSVLQIKEHSRETYSLLENPSHNV---LT--I 83
            :|..::||.|...:|:            |..:.....|::|.::..|. .|.|..||   ||  :
  Fly   239 DYRYIIGNLDWHTMDLEPYQHAGTNITGLRLVSPDSEQVQEVAKALYE-SEEPFQNVSCPLTNSM 302

  Fly    84 AFVNDSPEDILEILYRNLRMLNTQPV--------------LLVIRKSTIRVNSL-------LEWC 127
            |.|.|.    :::|....:.:|.:||              .||....::.:|.|       .|..
  Fly   303 ALVYDG----VQLLAETYKHVNFRPVALSCNDDSAWDKGYTLVNYMKSLTLNGLTGPIRFDYEGL 363

  Fly   128 WHHQLLKVVAIAQDFMESLIVYS-------YNPFPV--LQFIERRLDNSTVIFEKRLENLHGYEV 183
            .....|:|:.:|...|:.:..:|       ..|.|.  |:...|.|.|.:.:....:...:|
  Fly   364 RTDFKLEVIELAVSGMQKIGQWSGEDGFQENRPAPAHSLEPDMRSLVNKSFVVITAISEPYG--- 425

  Fly   184 PIALGGSSPRLIVYRDLEGKLIFSG----PVGNFMKSFEQRYNCRLVQPYPFDESAISP------ 238
              .|..:|.:      |||...|.|    .:....|.....|..||.:...:  ..|.|
  Fly   426 --MLKETSEK------LEGNDQFEGFGIELIDELSKKLGFSYTWRLQEDNKY--GGIDPKTGEWN 480

  Fly   239 --ARDLIAS-VQNGSVQIALGAIYPQVPYTGYSYPIELMSW--CLMMPVPEEVPHSQLYSMVFSP 298
              .|::|.| ...|...:.:    .....:|..:.|..||.  .::...|.:.| .:|:|.: ||
  Fly   481 GMLREIIDSRADMGITDLTM----TSERESGVDFTIPFMSLGIGILFRKPMKEP-PKLFSFM-SP 539

  Fly   299 MAFGITIVAMVLISLTLSMALRLHGYRVSFSEY----------------FLHDSCL---RGVLSQ 344
            .: |...:.:.|..:.:|:::.:.| |:|.:|:                |...:||   .|.|.|
  Fly   540 FS-GEVWLWLGLAYMGVSISMFVLG-RLSPAEWDNPYPCIEEPTELENQFSFANCLWFSIGALLQ 602

  Fly   345 SFYEVLRAPALIKAMYLVICLLGLLITSWYNSYFSTFVTSAPRFPQLTSYESIRHS----NIKIV 405
            ...|:.......:|:........|::.|.|.:..:.|:|.......:...:.:..:    |....
  Fly   603 QGSELAPKAYSTRAVAASWWFFTLILVSSYTANLAAFLTVESLVTPINDADDLSKNKGGVNYGAK 667

  Fly   406 IWKPEYEMLLFFSE-NMEKYSSIFQLQEDYKEFL--HLRDSFD----TRYGYMMPMEKWSLMKEQ 463
            |....:.   ||.| |...|..:::...|..:::  ..::..|    :.|.::|.
  Fly   668 IGGATFN---FFKESNYPTYQRMYEFMRDNPQYMTNTNQEGVDRVENSNYAFLME---------- 719

  Fly   464 QRVFSSPLFSLQDDLCVFHTVPIV-------FPMVKNSIFKEPFDRLILDVTATGLLSRWRDMSF 521
                |:.:..:.:..|....|..:       ..|.||..:::...:.:|::...|||::.:...:
  Fly   720 ----STTIEYITERRCTLTQVGALLDEKGYGIAMRKNWPYRDTLSQAVLEMQEQGLLTKMKTKWW 780

  Fly   522 TEMIKAGQLGLEDRGHPKEFRAMKVGDLIQIWRFVGWMLGLATIVFLLELI 572
            .|  |.|.....|........|:::.:|..::..:|........|.|||::
  Fly   781 QE--KRGGGACSDADEDSGAVALEISNLGGVFLVMGVGSFFGIFVSLLEMV 829

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir94d	NP_001138099.1	None
Grik	NP_001262788.1	PBP1_iGluR_Kainate	37..391	CDD:107377	32/156 (21%)
		ANF_receptor	53..374	CDD:279440	29/139 (21%)
		Periplasmic_Binding_Protein_Type_2	411..781	CDD:304360	70/407 (17%)
		Lig_chan	543..816	CDD:278489	47/292 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462868
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930