DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir94d and Ir7c

DIOPT Version :9

Sequence 1:	NP_001138099.1	Gene:	Ir94d / 7354412	FlyBaseID:	FBgn0259193	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_001245572.1	Gene:	Ir7c / 31692	FlyBaseID:	FBgn0029966	Length:	625	Species:	Drosophila melanogaster

Alignment Length:	554	Identity:	124/554 - (22%)
Similarity:	210/554 - (37%)	Gaps:	144/554 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 VNDSPEDILEILYR---NLRMLNTQPVLLVIRKSTIRVNSLLEWCWHHQLLKVVAIAQDFMESLI 147
            :.|.|.:.|:|::|   |:.:||..  :.:.|..|:.:.:...:..||           ...||.
  Fly   130 LEDQPMESLKIMFRRLLNMYVLNVN--VFLQRDGTVHLYTYYPYGPHH-----------CQSSLP 181

  Fly   148 VYSYNPFPVLQFIERRLDNSTVIFEKRLENLHGYEVPIALGGSSPRLIVYRD--LEGKLIFSGPV 210
            || |..|..|.........:..:|.::|.|:||.|:.:|.....|.:|:..|  ..|.....|..
  Fly   182 VY-YTAFQDLAAPANGFGLTKPLFPRKLTNMHGCEMVVATFEHRPYVIIEDDPKTPGGRSIHGIE 245

  Fly   211 GNFMKSFEQRYN--CRLVQPYPFDESAISPARD---LIASVQNGSVQIAL----------GAIYP 260
            |...:|..:|.|  .:||:....:...|.|..:   ::..:.:|.|.:..          ..:.|
  Fly   246 GLIFRSLAERMNFTIKLVEQKDKNRGEILPDGNFTGILKMMVDGEVNLTFVCFMYSKARSDLMLP 310

  Fly   261 QVPYTGYSYPIELMSWCLMMPVPEEV-PHSQL--------YSMVFSPMAFGITIVAMVLISLTLS 316
            ...||  |:||     .|::|....: |..:|        :|.:...:.||..::.::.|:....
  Fly   311 STSYT--SFPI-----VLVVPSGGSISPMGRLTRPFRYIIWSCILVSLIFGFVLICLLKITALPG 368

  Fly   317 MALRLHGYRVSFSEYFLHDSCLRGVLSQSFYEVLRAPALIKAMYLVICLLGLLITSWYNSYFSTF 381
            :...:.|.|.......:..|.|.|:       .|..|....|.|:::..|           ..|.
  Fly   369 LRNLVLGRRNRLPFMGMWASLLGGL-------ALYNPQRNFARYILVMWL-----------LQTL 415

  Fly   382 VTSAPRFPQLTSYESIR----HSNIKIV--IWKPEYEMLL------FFSENM--EKYSSIFQLQE 432
            :..|....||  |..::    .|.||.:  :...:||..:      .|.::|  ..:.::..|:|
  Fly   416 ILRAAYTGQL--YLLLQDVEMRSPIKSLSEVLAKDYEFRILPALRTIFKDSMPTTNFHAVLSLEE 478

  Fly   433 DYKEFLHLRD----------------SFDTRYGYMMPMEKWSLMKEQQRVFSSPLFSLQDDLCVF 481
               ....|||                .||.|.|   |      .|....|...||.
  Fly   479 ---SLYRLRDEDDPGITVALLQPTVNQFDFRSG---P------NKRHLTVLPDPLM--------- 522

  Fly   482 HTVPIVFPMVKNSIFKEPFDRLILDVTATGLLSRWRDMSFTEMIK--AGQLGLEDRGHPKEFRAM 544
             |.|:.|.|..:|.||...||||:.:.::|:::|:|.| :.:.||  :.:..||    ||.
  Fly   523 -TAPLTFYMRPHSYFKRRIDRLIMAMMSSGIVARYRKM-YMDRIKRVSKRRNLE----PKP---- 577

  Fly   545 KVGDLIQIWRFVGWML---GL---ATIVFLLELI 572
                 :.|||..|..:   ||   |.|||:||::
  Fly   578 -----LSIWRLSGIFVCCAGLYLVALIVFILEIL 606

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir94d	NP_001138099.1	None
Ir7c	NP_001245572.1	Lig_chan-Glu_bd	225..287	CDD:214911	13/61 (21%)
Ir7c	NP_001245572.1	Lig_chan	343..593	CDD:278489	65/305 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463049
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42643
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940