DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir94d and Grik3

DIOPT Version :9

Sequence 1:	NP_001138099.1	Gene:	Ir94d / 7354412	FlyBaseID:	FBgn0259193	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_001106187.1	Gene:	Grik3 / 298521	RGDID:	71027	Length:	919	Species:	Rattus norvegicus

Alignment Length:	256	Identity:	55/256 - (21%)
Similarity:	85/256 - (33%)	Gaps:	81/256 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 LPVSVLQIKEHSRETYSLLENPSHNVLTIAFVNDSPEDILEILYRNLRMLNTQPVLLVIRK---- 115
            |.||:|..|.:.       .|||    ..:|:|....||.  :|..|..|....||.||.:
  Rat   538 LGVSILYRKPNG-------TNPS----VFSFLNPLSPDIW--MYVLLAYLGVSCVLFVIARFSPY 589

  Fly   116 -----------STIRVN--SLLEWCWH---------HQLL------KVVAIAQDFMESLIVYSYN 152
                       |.:..|  :||...|.         .:|:      :::.....|...:|:.||.
  Rat   590 EWYDAHPCNPGSEVVENNFTLLNSFWFGMGSLMQQGSELMPKALSTRIIGGIWWFFTLIIISSYT 654

  Fly   153 ----PFPVLQFIERRLDN------------------STVIFEKRLENLHGYEVPIALGGSSPRLI 195
                .|..::.:|..:|:                  :|:.|.|: ..:..:|...|...|.|..:
  Rat   655 ANLAAFLTVERMESPIDSADDLAKQTKIEYGAVKDGATMTFFKK-SKISTFEKMWAFMSSKPSAL 718

  Fly   196 VYRDLEG-KLIFSGPVGNFMKSFEQRY----NCRLVQ--------PYPFDESAISPARDLI 243
            |..:.|| :...:......|:|....|    ||.|.|        .|.......||.||.|
  Rat   719 VKNNEEGIQRTLTADYALLMESTTIEYITQRNCNLTQIGGLIDSKGYGIGTPMGSPYRDKI 779

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir94d	NP_001138099.1	None
Grik3	NP_001106187.1	PBP1_iGluR_Kainate_GluR5_7	34..417	CDD:107388
		ANF_receptor	55..398	CDD:279440
		PBP2_iGluR_Kainate_GluR7	433..801	CDD:270441	55/256 (21%)
		Lig_chan	564..832	CDD:278489	45/219 (21%)
		Glutamate binding	690..692		0/1 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350186
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840