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Protein Alignment Ir94d and Grin2a

DIOPT Version :9

Sequence 1:	NP_001138099.1	Gene:	Ir94d / 7354412	FlyBaseID:	FBgn0259193	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_036705.3	Gene:	Grin2a / 24409	RGDID:	2737	Length:	1464	Species:	Rattus norvegicus

Alignment Length:	679	Identity:	116/679 - (17%)
Similarity:	218/679 - (32%)	Gaps:	279/679 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 QLHLLLVALVLLSPGGDSFYHSLIHHLNRELKIEYVLLLGNFDTTWLDI---LWQLPVSVLQIKE 64
            |:|..||.:|                ||::.:.|.|   |.::...|.:   :|.
  Rat   356 QVHPRLVVIV----------------LNKDREWEKV---GKWENQTLSLRHAVWP---------- 391

  Fly    65 HSRETYSLLENPSHNVLTIAFVNDSPEDILEILYRNLRMLNTQPVLLVIRKSTIRVNSLLEWCWH 129
             ..:::|..| |..|.|:|..:.::|..|:|                       .::.|.|.|..
  Rat   392 -RYKSFSDCE-PDDNHLSIVTLEEAPFVIVE-----------------------DIDPLTETCVR 431

  Fly   130 HQLLKVVAIAQDFMESLIVYSYNPFPVLQFIERRLDNST--------------VIFEKRLENL-- 178
                                  |..|..:|:  :::|||              :...|:|...
  Rat   432 ----------------------NTVPCRKFV--KINNSTNEGMNVKKCCKGFCIDILKKLSRTVK 472

  Fly   179 HGYEVPIALGGSSPRLI--VYRDLEGKLIFSG---PVGNFMKSFEQRYNCRLVQ-PYPFDESAIS 237
            ..|::.:...|...:.:  |:..:.|::::..   .||:...:.|:   ..:|. ..||.|:.||
  Rat   473 FTYDLYLVTNGKHGKKVNNVWNGMIGEVVYQRAVMAVGSLTINEER---SEVVDFSVPFVETGIS 534

  Fly   238 PARDLIASVQNGSVQIALGAIYPQVPYTGYSYPIELMSWCLMMPVPEEVPHSQLYSMVFSPMAFG 302
                ::.|..||:|.                                  |     |....|.:..
  Rat   535 ----VMVSRSNGTVS----------------------------------P-----SAFLEPFSAS 556

  Fly   303 ITIVAMVLISLTLSMALRLHGYRVSFSEYFLHDSCLRGVLSQSFYEVLRAP-----ALIKAMYLV 362
            :.::..|::.:..::|:.:..|   ||....:.:..:|          :||     .:.||::|
  Rat   557 VWVMMFVMLLIVSAIAVFVFEY---FSPVGYNRNLAKG----------KAPHGPSFTIGKAIWL- 607

  Fly   363 ICLLGLLITSWYNSYFSTFVTSAP-RFPQLTSYESIRHSNIKIVIWKPEYEMLLF---FSENMEK 423
              |.||:           |..|.| :.|:.|:      |.|.:.:|  .:..::|   ::.|:
  Rat   608 --LWGLV-----------FNNSVPVQNPKGTT------SKIMVSVW--AFFAVIFLASYTANL-- 649

  Fly   424 YSSIFQLQEDY---------KEFLHLRD-----SFDT------------RYGYMMPMEKWSLMKE 462
              :.|.:||::         |:|....|     .|.|            .|.||...    :.:.
  Rat   650 --AAFMIQEEFVDQVTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNNYPYMHQY----MTRF 708

  Fly   463 QQRVFSSPLFSL--------------------QDDLC---------VFHTVPIVFPMVKNSIFKE 498
            .||.....|.||                    :|:.|         :|.|......:.|.|.:|.
  Rat   709 NQRGVEDALVSLKTGKLDAFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGSPWKR 773

  Fly   499 PFDRLILDVTATGLLSRWRDMSFTEMIKAGQLGLEDRGHPKEFRAMK----VGDLIQIWRFVGWM 559
            ..|..:|.....|           ||.:...|.|....|.::...|.    :.::..::..:...
  Rat   774 QIDLALLQFVGDG-----------EMEELETLWLTGICHNEKNEVMSSQLDIDNMAGVFYMLAAA 827

  Fly   560 LGLATIVFLLELICFWRHKMWQNMKYMFC 588
            :.|:.|.|:.|.:.:|        |..||
  Rat   828 MALSLITFIWEHLFYW--------KLRFC 848

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.